PREVALENCE OF WHEAT ALLERGY IN AL-KHARJ, SAUDI ARABIA

Authors

  • Ali S. Al- Ghonaim
  • Saad R. Al- Qassam
  • Omar Kujan
  • Bassel Tarakji
  • Azzegahiby S
  • Azzegahiby I
  • Richard K.H. Wyse
  • Mohammed W. Al- Rabia
  • Faris Q.B. Alenzi

Abstract

Background: Wheat allergy has been suggested to represent an important allergic disease. This study collates clinical and laboratory aspects in patients with wheat allergy in Al-Kharj city, Saudi Arabia. Methods: Total and specific IgE were measured in 15 suspected cases of wheat allergy. Protein allergenicity was assessed with Western blotting. Results: Significant elevation of total and specific IgE was found in 4 cases. Basophlia was also demonstrated on blood film. Western blotting results showed 2 bands (83 and 40 kDa). Conclusion: Wheat allergy must also be considered when planning treatment of asthma and eczema of adult patients.Keywords: Allergy, IgE, Asthma, Eczema, Wheat, Saudi Arabia

References

El-Rab MO. Foods and food allergy: the prevalence of IgE antibodies specific for food allergens in Saudi patients. Saudi J Gastroenterol 1998;4(1):25–9.

Nepper-Christensen S, Backer V, DuBuske LM, Nolte H. In vitro diagnostic evaluation of patients with inhalant allergens. Summary of probability outcomes comparing results of CLA- and CAP- specific IgE test systems. Allergy Asthma Proc 2003;24(4):253–8.

Nolte H, DuBuske LM. Performance characteristics of a new automated enzyme immunoassay for the measurement of allergen-specific IgE. Summary of the probability outcomes comparing results of allergen skin testing to results obtained with the HYTEC system and CAP system. Ann Allergy Asthma Immunol 1997;79(1):27–34.

Nielsen IP, Ostergaard PA, Harris RI, Gammelby P. Comparison of CLA with BPT, SPT and RAST in children. Allergy 1992;47(1):30–4.

Williams PB, Dolen WK, Koepke JW, Seiner JC. Comparison of skin testing and three in vitro assays for specific IgE in the clinical evaluation of immediate hypersensitivity. Ann Allergy 1992;68:35–45.

Kelso JM, Sodhi N, Gosselin VA, Yunginger JW. Diagnostic performance characteristics of the Phadebas RAST, modified RAST, and Pharmacia CAP system versus skin testing. Ann Allergy 1991;67:511–4.

Brown CR, Higgins KW, Frazer K, Schoelz LK, Dyminski JW, Marinkovich VA, et al. Simultaneous determination of total IgE and specific IgE in serum by the MAST Chemiluminescent Assay System. Clin Chem 1985;31:1500–5.

Al-Hussaini A, Semaan T, El Hag I. Eosinophilic esophagitis in a developing country: Is it different from developed countries? Gastroenterol Res Pract 2013;2013:526037. doi: 10.1155/2013/ 526037.

Published

2013-06-01

Issue

Vol. 25 No. 1-2 (2013): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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