ASSOCIATION OF QUALITY OF SLEEP WITH COGNITIVE DECLINE AMONG THE PATIENTS OF CHRONIC KIDNEY DISEASE UNDERGOING HAEMODIALYSIS

Authors

  • Usama Bin Zubair PIMS
  • Batool Butt CMH RWP

Abstract

Background: This study was conducted to determine the association between the subjective quality of sleep and cognitive decline among the patients of chronic kidney disease (CKD) undergoing haemodialysis. Methods: In this cross-sectional study 106 patients of chronic kidney disease (CKD) undergoing haemodialysis at a tertiary care hospital in Rawalpindi, Pakistan were included in the final analysis. Cognitive decline was measured by British Columbia Cognitive Complaints Inventory (BC-CCI). Sleep quality was measured by using the Pittsburgh Sleep Quality Index (PSQI). Relationship of age, gender, marital status, education, occupation, BMI, duration of dialysis, dialysis count per week, family income, tobacco smoking and use of naswar was assessed with the cognitive decline. Results: Out of 106 patients screened through BC-CCI and PSQI, 13.1% had no cognitive decline while 86.9% had significant cognitive decline. Relationship between quality of sleep and cognitive decline was significant on binary logistic regression. Conclusion: This study showed significant relationship between the sleep quality and cognitive decline among the patients of CKD undergoing haemodialysis. The findings of our study also call for a greater degree of understanding of the physical and psychological state of patients of CKD undergoing haemodialysis.Keywords: sleep quality; Cognitive decline; Haemodialysis; PSQI; BC-CCI

References

U.S. Renal Data System Annual Data Report (2015), Centers for Medicare & Medicaid Services. [Internet]. [cited 2017 Feb 15]. Available from: https://www.usrds.org/2015/download/vol2_USRDS_ESRD_15.pdf

Gerogianni SK, Babatsikou FP. Psychological Aspects in Chronic Renal Failure. Health Sci J 2014;8(2):205–14.

Rodríguez-Angarita CE, Sanabria-Arenas RM, Vargas-Jaramillo JD, Ronderos-Botero I. Cognitive impairment and depression in a population of patients with chronic kidney disease in Colombia: a prevalence study. Can J Kidney Health Dis 2016;3:26.

Madan P, Karla OP, Agarwal S, Tandon OP. Cognitive impairment in chronic kidney disease. Nephrol Dial Transplant 2007;22(2):440–4.

Moreira JM, da Matta SM, Melo e Kummer A, Barbosa IG, Teixeira AL, Simoes e Silva AC. Neuropsychiatric disorders and renal diseases: an update. J Bras Nefrol 2014;36(3):396–400.

Parvan K, lakdizaji S, Roshangar F, Mostofi M. Quality of Sleep and its Relationship to Quality of Life in Hemodialysis Patients. J Caring Sci 2013;2(4):295–304.

Tell H. Determining Quality of Life and Sleep in Hemodialysis Patients. Dial Transplant 2009;38(6):210–5.

Kutner NG, Zhang R, Huang Y, Bliwise DL. Association of sleep difficulty with Kidney Disease Quality of Life cognitive function score reported by patients who recently started dialysis. Clin J Am Soc Nephrol 2007;2(2):284–9.

Yaffe K, Falvey CM, Hoang T. Connections between sleep and cognition in older adults. Lancet Neurol 2014;13(10):1017–28.

Iverson GL, Lam RW. Rapid screening for perceived cognitive impairment in major depressive disorder. Ann Clin Psychiatry 2013;25(2):135–40.

Menon VB, Alla P, Madhuri S, Sanathan SR, Shetty MS, Ram D, Sleep Quality in End-Stage Renal Disease Patients on Maintenance Hemodialysis: A Six Month Prospective Survey. Int J Pharm Sci Res 2015;6(2):660–8.

Hashmi AM, Khawaja IS, Butt Z, Umair M, Naqvi SH, Jawad-Ul-Haq. The Pittsburgh Sleep Quality Index: validation of the Urdu translation. J Coll Physicians Surg Pak 2014;24(2):123–6.

Poverty and social safety nets. Chapter 15. Pakistan economic survey 2013-14. [Internet]. [cited 2017 Feb 15]. Available from: http://finance.gov.pk/survey/chapters_14/15_Poverty_Social_Safety_Nets.pdf

Sabet R, Naghizadeh MN, Azari S. Quality of sleep in dialysis patients. Iran J Nurs Midwifery Res 2012;17(4):270–4.

Imran S, Shiekh A, Saeed Z, Khan SA, Malik AO, Patel J, et al. Burden of chronic kidney disease in an urban city of Pakistan, a cross-sectional study. J Pak Med Assoc 2015;65(4):366–9.

Yaqub S, Kashif W, Raza MQ, Aaqil H, Shahab A, Chaudhary MA, et al. General practitioners' knowledge and approach to chronic kidney disease in Karachi, Pakistan. Indian J Nephrol 2013;23(3):184–90.

Agganis BT, Weiner DE, Giang LM, Scott T, Tighiouart H, Griffith HL, et al. Depression and Cognitive Function in Maintenance Hemodialysis Patients. Am J Kidney Dis 2010;56(4):704–12.

Rai M, Rustagi T, Rustagi S, Kohli R. Depression, insomnia and sleep apnea in patients on maintenance hemodialysis. Indian J Nephrol 2011;21(4):223–9.

Nutt D, Wilson S, Paterson L. Sleep disorders as core symptom of depression. Dialogues Clin Neurosci 2008;10(3):329–36.

Keefe RS. Treating cognitive impairment in depression: an unmet need. Lancet Psychiatry 2016;3(5):392–3.

Published

2017-10-15

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