COMPARISON OF MEASLES COMPLICATIONS IN WELLNOURISHED AND MAL-NOURISHED CHILDREN

Imran Qaisar, Ameer Ahmad, Fiaz Ahmad, Atta ullah Mazhar

Abstract


Background: Measles is the most common and the most infectious of the viral infections of childhood.
It can cause severe pneumonia, diarrhoea, encephalitis, and death. A significant proportion of deaths
due to measles in young children worldwide are attributable to low weight for age. To compare the
measles complications in well-nourished and mal-nourished children, this cross-sectional study was
conducted at Paediatric out-patient department and paediatric unit 1 Bahawal Victoria Hospital
Bahawalpur. Methods: Total 120 patients were included in the study. All patients presented with signs
and symptoms suggestive of measles according to WHO criteria. These patients were divided into wellnourished and malnourished according to the modified Gomez classification. Both groups were
evaluated for measles complications like pneumonia, diarrhoea, encephalitis, corneal ulceration,
thrombocytopenia, otitis media and myocarditis by detailed history and complete physical examination,
and statistically analysed. Results: In the studied patients, 75 were males and 45 were females. Mean
age was 23 months. Fifty-nine (49.2%) patients were well-nourished and 61 (50.8%) were
undernourished. Fifty-two (43.3%) patients were having pneumonia. Fifty-three (44.2%) patients were
having diarrhoea. Twenty-six (21.7%) patients were having encephalitis. Corneal ulceration was found
in 9 (7.5%) patients. Thrombocytopenia and otitis media was present in 1 patient in each group.
Fourteen patients expired. Conclusion: Measles is a global epidemic problem having many serious
complications, including pneumonia, diarrhoea, encephalitis, corneal ulcerations etc. Moreover these
complications are more frequent in under nourished children. Efforts should be made to improve the
nutritional status of the children and to eradicate this disease by effective vaccination.
Keywords: Measles, well-nourished, under-nourished, pneumonia, encephalitis, diarrhoea,
complications, vaccination, mortality

Full Text:

PDF

References


Measles-United Stated, 2004. U.S. National Library of Medicine

National Institute of Health. MMWR, Morb Mortal Wkly Rept.

;54:1229–31.

Stein EC, Birmingham M, Kurain M, Duclos P, Strebel P. The global

burden of measles in the year 2000: a model that uses country-specific

indicators. J Infect Dis 2003;187( suppl 1):S8–S14.

Khan EA. Targeting Zero measles in Pakistan: Time to change the

EPI Schedule. Infect Dis J 2003;12:87–90.

Aurangzeb B, Nisar YB, Hazir T, Burki F, Hassan M. Clinical

outcome in children hospitalized with complicated measles. J Coll

Physician Surg Pak 2005;15:547–51.

Caulfield LE, de Onis M, Blossner M, Black RE. Undernutrition as

an underlying cause of child deaths associated with diarrhea,

pneumonia, malaria and measles. Am J Clin Nutr 2004;80:193–8.

Global measles mortality reduction and regional elimination 2000–

; Canada Communicable Disease Report May 15 2002. p28.

Ota MO, Moss WJ, Griffin, DE. Emerging diseases: measles. J

Neurovirol 2005;11:447–54.

Kerdiles YM, Sellin CI, Druelle J, Horvat B. Immunosuppresion

caused by measles virus: role of viral proteins. Rev Med Virol

;16:49–63.

Ariyasriwatana C, Kalayanarooj S. Severity of measles: a study at

the Queen Sirikit National Institute of Child Health. J Med Assoc

Thai 2004;87:581–8.

Younas M, Iqbal I, Noreen N. Complications of measles and risk

factor for mortality. Pak Paed J 2003;27:35–9.

Tariq P. Assessment of coverage levels of single dose measles

vaccine. J Coll Physician Surg Pak 2003;13:507–10.

Caksen H, Odabas D, Sar S, Tuncer O, Atas B. Measles is still a

severe problem in Eastern Turkey. J Med Assoc Thai 2004;87:386–8.

Dietz V, Spika J, Kezaala R, Moshni E, Thapa A, Macfarland J, et al.

Update: global measles control and mortality reduction-world wide,

–2001. MMWR Morb Mortal Wkly Rept.2003;52:471–5.

Henao-Restripo AM, Strebel P, Hoekstra EJ, Birmingham M,

Bilous J. Experience in global measles control, 1990–2001. J Infect

Dis 2003;187(suppl):s15–s21.


Refbacks

  • There are currently no refbacks.


Contact Number: +92-992-382571

email: [jamc] [@] [ayubmed.edu.pk]