CLINICOHISTOLOGICAL PATTERN OF OVARIAN TUMOURS IN PESHAWAR REGION

Authors

  • Sumaira Yasmin
  • Aiman Yasmin
  • Mohammad Asif

Abstract

Background: Ovarian tumours are one of the major health problems confronting the generalpractitioners in general and gynaecologists in particular. Ovarian tumours may either beasymptomatic, found on the routine ultrasound examination or symptoms may be vague till thepatient has an acute emergency like torsion or rupture of a benign cyst. The worst is late presentationof a malignant ovarian tumour. There is marked variation in the presentation of the tumour as well asin histological types. This study was undertaken to analyse modes of presentation and varioushistopathological patterns of ovarian tumours. Methods: This study was conducted from 1st January,2002 to 31st December, 2002, in Gynaecology ‘A’ Unit, Lady Reading Hospital (LRH) Peshawar.After admitting patients with ovarian tumours a detailed case history was taken followed by thoroughclinical examination. All the relevant details were recorded using the questionnaire. Patients wereinvestigated after performing various surgical procedures; the specimens of ovarian tumours weresubjected to Histopathological examination in the histopathology section, Lady Reading Hospital,Peshawar. Results: Amongst the total numbers of 5732 gynaecological admissions during studyperiod the total numbers of ovarian tumours were sixty-eight. Out of which benign ovarian tumourswere 61 (89.71%) and malignant ovarian tumours were 7 (10.29%) There were no tumours withborderline malignancy. The commonest histological pattern observed in the study was epithelialtumours (76.5%) including both benign and malignant tumours. The commonest benign tumour wasserous cyst adenoma (24%) followed by mature cystic teratoma (18%). Common malignant ovariantumours were granulosa cell tumours and Endometriod carcinoma (each 28.5%). Conclusion:Epithelial tumours are the commonest variety of ovarian tumours followed by Germ cell tumours.The histological type of ovarian tumour correlates with the prognosis of the tumour.Keywords: Ovarian tumours, teratoma, adenoma, cystadenoma, metastatic, neoplasm

References

Parveen S, Ilyas N, Asghar S. Patterns of care for ovarian cancer:

Patients at Institute of Nuclear Medicine and Oncology (INMOL)

Lahore. Specialist J Pak Med. Sci 1999;15:209–15

SenU, Sankaranarayanan R, Mandal S, Romana AV, Parkin DM,

Siddique M. Cancer patterns in Eastern India: The first report of

Kalkata Cancer Registry. Int J Cancer 2002;100:86–91.

Murad A. Ovulation induction and ovarian tumours: the debate

continues. J Pak Med Assoc 1998;48:353-6.

TortoleroL, Mitchell FM, Rhodes HE. Epidemiology and

screening of ovarian cancer. Obstet Gynaecol Clin North Am

;21:63–75.

Day N.E, Krishnan E. Epidemiology of gynaecological cancers.

Gynaecology by Shaw R W. 2nd ed. Edinburgh: Churchill Living

Stone, 1997; p. 477–87.

Piver MS. Prophylactic Oophorectomy: Reducing the U.S. Death

Rate from Epithelial Ovarian Cancer. A Continuing Debate.

Oncologist 1996;1:326–30

Rashid S, Sarwar G, Ali A. A clinicopathological Study of

ovarian cancer. Departments of Radiotherapy and oncology Sir

Ganga Ram Hospital and Mayo Hospital Lahore. J Pak Med

Assoc 1998;36;117–25.

Jamal S, Quddusi H, Mehmood A. A Clinico Histopathological

analysis of 110 ovarian tumours. Pak J Med Sci 1997;14:19–23.

Sasaki H, Oda M, Ohmura M, Akiyama M, Liv C ,ganes SV et al.

Follow up of women with simple ovarian cysts detected by

transvaginal sonography in the Tokyo matropoliton area. Br J

Obst Gynaecol 1999; 415–20.

Fishman DA, Cohen L, Blank SV, Shulman L,Singh D,Bozorgi

K et al. The role of ultrasound evaluation in the detection of

early-stage epithelial ovarian cancer. Am J Obstet Gynecol

;192:1214–21.

Thanikasalam K, Ho CM, Adeed N, Shahidan MN, Azizah WK.

LinksPattern of ovarian tumours among Malaysian women at

General Hospital, Kuala Lumpur. Med J Malaysia 1992;47:139–46.

Prabarker, Maingi K. Ovarian tumours--prevalence in Punjab.

Indian J pathol Microbiol 1989;32:276–81.

Jordan SJ, Green AC, Whiteman DC, Webb P M. Australian

Ovarian Cancer Study Group. Risk factors for benign, borderline

and invasive mucinous ovarian tumors: epidemiological evidence

of a neoplastic continuum? Gynecol Oncol 2007;107:223–30.

Ahmed Z, Kiyani N, Hasan S. H, Muzaffar S. Gill M. S.

Histological Patterns of ovarian neoplasia. J Pak Med Assoc

;50:416–9.

Pilli GS, Suneeta KP, Dhaded AV, Yenni VV. Ovarian tumours:

a study of 282 cases: J Indian Med Assoc 2002;100:420, 423–4.

Barakat R.R. Borderline tumours of the ovary. Obstet Gynaecol

Clin North Am 1994;21:93–105.

Gupta N, Bisht D, Agarwal AK, Sharma VK. Retrospective and

rospective study of ovarian tumours and tumour-like lesions:

Indian J Pathol Microbiol. 2007;50(3):525–7.

Published

2008-12-01