RELATION OF BODY MASS INDEX WITH LIPID PROFILE AND BLOOD PRESSURE IN YOUNG HEALTHY STUDENTS AT ZIAUDDIN MEDICAL UNIVERSITY

Jawed Aziz, Nadeem A Siddiqui, Imran A Siddiqui, Amir Omair

Abstract


Background: This study was conducted to assess serum lipids in healthy young subjects in relation with their BMI. Methods: Students of Ziauddin Medical University were assessed for anthropometric measures, blood pressure and lipid profile at the time of their admission for MBBS program. Results: Out of 426 students all parameters were available for 301 students and they were selected for analysis in this study. Mean serum cholesterol in 301students was 149.3 ±31.3 mg/dl, mean LDL-C was 91.3 mg/dl ±27.7, mean HDL-C was 40.0 mg/dl ±42.2, mean triglycerides were 89.9 mg/dl ±42.2, mean systolic blood pressure was 113.1 mmHg ±13.5 and mean diastolic blood pressure was 74.0 mmHg ±8.1. The mean BMI of students was 21.6 Kg/m2 ±4.2. Among 301 students, 88 were underweight, 175 were normal and 38 were overweight according to their BMI. We found no significant difference in mean serum cholesterol and LDL-C while there were significant difference in mean serum HDL-C, triglycerides, systolic and diastolic blood pressure among the three BMI groups. Conclusion: In our study, there are high numbers of at-risk individuals. Therefore, strategies should be designed for weight reduction in children and adults to prevent cardiovascular disease.Keywords: Body Mass Index, Lipid Profile, Healthy students  

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References


Hashmi JA. An epidemiological study of heart disease in Pakistan. J Pak Med Assoc 1965;15:39-41.

Nisar F, Din S, Jabeen M. Serum cholesterol of children of various socio-economic groups. Pak J Med Res 1985; 15: 117-21.

Gordon T. Coronary heart disease in young women: Incidence and Epidemiology. In Oliver MF, ed. Coronary heart disease in young women. Edinburgh: Churchill Livingstone, 1978.

Kannel WB. A general cardiovascular risk profile. The Framingham study. Am J Cardiol 1976;38:46-51.

Stamler J, Epstein FH. Coronary heart disease risk factors as guide to preventive action. Prev Med 1972; 1: 27-30.

Epstein FH. The Tecumseh study: Design, progress and prospects. Arch Environ Health 1970;21:402-6.

Lipid Research Clinic Program. The lipid research clinic coronary primary prevention trial results II. J Am Med Assoc 1984; 251: 364-74.

Fogelman A, Schechter I, Seager J. Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages. Proc Natl Acad Sci USA 1980;77: 2214-8.

Palinski W, Rosenfeld M, Yla-Herttuala S. Low density lipoprotein undergoes oxidative modification in vivo. Proc Natl Acad Sci USA 1989; 86:1372-6.

Witztum JL, Steinberg D. Role of oxidized low density lipoproteinin atherogenesis. J Clin Invest 1991;88:1785-92.

Khoo KL, Tan H, Leiw YM. Serum lipids and their relationship with other coronary risk factors in healthy subjects in a city clinic. Med J Malaysia 1997; 52: 38-52.

Tao S, Li Y, Xiao Z, Cen R, Zhang H, Zhuo B, Chen P, Li Y, Liao Y. Serum lipids and their correlates in Chinese urban and rural population of Beijing and Guangzhou. PRC-USA Cardiovascular and Cardiopulmonary Epidemiology Research Group. J Epidemiol 1992; 21: 893-903.

Hart C, Ecob R, Smith GD. People, places and coronary heart disease risk factors: a multilevel analysis of the Scottish Heart Health Study archive. Soc Sci Med 1997; 45: 893-902.

Vartiainen E, Pekkanen J, Koskinen S, Jousilahti P, Salomma V, Puska P. Do changes in cardiovascular risk factors explain the increasing socioeconomic difference in mortality from ischaemic heart disease in Finland? J Epidemiol Community Health 198l; 52: 416-9.

Shahid A, Zuberi SJ, Hasnain N. Lipid pattern in healthy subjects. Pak J Med Res 1985; 24: 33-7.

Malik R, Pirzado ZA, Ahmed S, Sajid M. Study of lipid profile, blood pressure and blood glucose in rural population. Pak J Med Res 1995; 34: 152-5.

Prineas RJ, Gillum RF, Horibe H, Hannan PJ, Stat. The Minneapolis Children’s Blood Pressure Study: standards of measurement for children’s blood pressure. Hypertention 1980;2(suppl I): S18-24.

Sinaiko AR, Donahue RP, Jacobs DR, Prineas RJ. Relation of weight and rate of increase in weight during childhood and adolescence to body size, blood pressure, fasting insulin and lipids in young adults. Circulation 1999; 99: 1471-6.

Donahue RP, Orchard TJ, Kuller LH, Drash AL, Lipids and lipoproteins in young adult population. Am J Epidemiol 1985;240:458-67.

DeFronzo RA, Ferrannini E. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. Diabetes Care 1991;14:173–94.

Lind L, Lithell H, Pollare T. Is it hyperinsulinemia or insulin resistance that is related to hypertension and other metabolic cardiovascular risk factors? J Hypertens 1993; 11(suppl 4): S11–6.

Morris AD, Petrie JR, Connell JMC. Insulin and hypertension. J Hypertens 1994; 12: 633–42.

Godsland IF, Stevenson JC. Insulin resistance: syndrome or tendency? Lancet 1995; 346: 100–03.

Manson JE, Tosteson H, Ridker PM, Satterfield S, Hebert P, O'Connor GT, et al. The primary prevention of myocardial infarction. N Engl J Med 1992;326:1406–16.

DiPietro L, Mossberg HO, Stunkard AJ. A 40 year history of overweight children in Stockholm: life-time overweight, morbidity, and mortality. Int J Obes 1994; 18: 585–90.


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