S.P. Khan, A. Waheed, J.A Khan, Aniqa Bano


We have studied ionized serum calcium, total calcium, phosphorus, total protein and albumin
in 20 normal pregnant women, 37 moderate and severe pregnancy induced hypertensive women and
9 pregnant women with chronic hypertension. The total serum calcium was significantly reduced in
moderate and severe pregnancy induced hypertension and chronic hypertension (P<0.05 and 0.0001
respectively) while ionized calcium was also significantly reduced in pregnancy induced
hypertension and chronic hypertension patients as compared to the normotensive pregnant women.
(P<0.001 and P<0.0001 respectively). Total protein and albumin was less in hypertensive group as
compared to normotensive. Serum phosphate was increased in hypertensive group.
It was observed that total calcium and ionized calcium among these hypertensive groups were
decreased which support conclusion of other epidemiologic studies of hypertension in non-pregnant
patients and pregnant patients that abnormal calcium metabolism contributes to the genesis of

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