CUTANEOUS LEISHMANIASIS: AN EMERGING CHILDHOOD INFECTION

Shaheen Shoaib, Shoaib Tauheed, Amtul Hafeez

Abstract


Background: Cutaneous Leishmaniasis (CL) has been an endemic parasitic infection in certain
areas of Pakistan. New outbreaks have occurred in many areas not identified previously especially
in the province of Sindh. The object of this study was to see the prevalence of CL as a childhood
disease. Methods: It was a cross sectional study in which 400 cases coming to various skin
disease clinics were included for confirmation of CL by microscopy, culture and PCR. Results:
Out of 400 cases, 185 cases of ages from 1–14 years were diagnosed clinically and confirmed by
Lab. Tests for CL. Both dry and wet types of lesions were observed that indicated presence of
more than one strain of the parasite. Conclusion: Cutaneous Leishmaniasis was found to be
significantly prevalent in children. The strains were found to be L. tropica and L. major as was
indicated by the nature of lesions and confirmed by PCR.
Keywords: Cutaneous leishmaniasis, Childhood infection, L. tropica, L. major.

Full Text:

PDF

References


WHO Control of Leishmaniasis. WHO Technical report

series. No. 793,1990.

Mujtaba G, Khalid M. Cutaneous leishmaniasis in Multan,

Pakistan. Int J Dermatol 1998;37(11):843–5.

Bhutto AM, Soomro RA, Nonaka S. Detection of new

endemic areas of cutaneous Leishmaniasis in Pakistan. A 6

year study. Int J Dermatol 2005;42 (7)47–8.

Strohl AW, Rouse H, Fisher BD. Microbiology. 2nd ed.

Philadelphia: Lippincot Williams and Wilkins;2001.

Cheesebrough M. Medical Laboratory Manual for tropical

countries. 1stEd Cambridge University press;1984.

Fleck SL, Moody AH. Diagnostic techniques in medical

Parasitology (1st Ed) Cambridge University Press;1993.

Hassan Q, Ghosh A, Ghosh A. Enzymatic amplification of

miniexon derived RNA gene spacers of Leishmania

donorani. Parasitology 1993;107:509–17.

Sharma NL, Mahajan VK, NegiAle. Epidemiology of a new

focus of localized cutaneous leishmaniasis. Himachal

Pradesh. J Commun Dis 2005;37(4):257–9.

Kharfi M, Benmously R, El Fekih. Childhood Leishmaniasis.

Dermatology online J 2004;10(2):6.

Talari SA, Talaei R, Shajari G. Childhood cutaneous

leishmaniasis. Report of 117 cases from Iran. Korean J

Parasitol 2006;44(4):355–60.

Chargui N, Bastien P, Kallel K. Usefulness of PCR in the

diagnosis of cutaneous leishmaniasis. Trans R Soc Trop Med

Hyg 2005;99(10):762–8.

Romero GA, Guerra MV, Paes MG. Sensitivity of the

polymerase chain reaction for the diagnosis of cutaneous

leishmaniasis due to Leishmania (Viannia) guyanensis. Acta

Trop 2001;79(3):225–9.


Refbacks

  • There are currently no refbacks.


Contact Number: +92-992-382571

email: [jamc] [@] [ayubmed.edu.pk]