VITAMIN D INTOXICATION IN 7-MONTH-OLD INFANT WITH RECOMMENDED DAILY INTAKE OF VITAMIN D

Nadia Waheed, Huma Arshad Cheema, Anjum Saeed, Muhammad Arshad Alvi, Zafar Fayyaz, Nadeem Anjum, Sara Batool

Abstract


Over the past decade there is increased use of vitamin D supplementation because of its benefits on bone health. It is a fat-soluble vitamin and cannot be excreted from the body. There is need for monitoring 25-hydroxyvitamin D levels in infants and children who receive long-term vitamin D supplementation at or above the upper level intake that is currently recommended. Vitamin D intoxication can present from mild ignorable to severe life-threatening symptoms. We present a 7-month-old infant with vitamin D intoxication at recommended daily doses of vitamin D.

Keywords: Hypervitaminosis D; Recommended daily allowance; Hypercalcemia, Vitamin D

References


Vanstone MB, Oberfield SE, Shader L, Ardeshirpour L, Carpenter TO. Hypercalcemia in children receiving pharmacologic doses of vitamin D. Pediatrics 2012;129(4):e1060–3.

Gallo S, Comeau K, Vanstone C, Agellon S, Shama A, Hones G, et al. Effect of different dosages of oral vitamin D supplementation on vitamin D status in healthy, breastfed infants: a randomized trial. JAMA 2013;309(17):1785–92.

Abrams SA, Hawthorne KM, Chen Z. Supplementation with 1000 IU vitamin D/d leads to parathyroid hormone suppression, but not increased fractional calcium absorption, in 4–8-y-old children: a double-blind randomized controlled trial. Am J Clin Nutr 2013;97(1):217–23.

Fraser WD, Milan AM. Vitamin D assays: past and present debates, difficulties, and developments. Calcif Tissue Int 2013;92(2):118–27.

Sanders KM, Nicholson GC, Ebeling PR. Is high dose vitamin D harmful? Calcif Tissue Int 2013;92(2):191–206.

LeBlanc ES, Perrin N, Johnson JD Jr, Ballatore A, Hillier T. Over-the-counter and compounded vitamin D: is potency what we expect? JAMA Intern Med 2013;173(7):585–6.

Sezer RG, Guran T, Paketçi C, Seren LP, Bozaykut A, Bereket A. Comparison of oral alendronate versus prednisolone in treatment of infants with vitamin D intoxication. Acta Paediatr 2012;101(3):122–5.


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