ANEMIA IN CHRONIC RENAL FAILURE
Abstract
Anaemia in chronic renal failure (CRF) is almost universal abnormality. Sixty diagnosed cases of i. 'RF wereincluded in this study which included patients of peritoneal and haemodialysis. anemia of variable degree was presentin almost all the patients and its incidence was same in both groups. The mean pre-dialysis haemoglobin (lib) was 7.4g dl. After dialysis slight increase in HB occurred, the increase was more in, patients on haemodialysis. The postdialysis mean lib level was S.3 g dl. Similar changes occurred in R.B(count and packed cell Volume (PVC). The predialysis sample in IS. 13% showed reticulocytosis and the mean Retie. Count was 1.5%. Vo changes in mean Retiecount occur after dialysis. The presence of burr cells and fragmented RBC was the commonest red cellsmorphological abnormality observed in our patents. Dialysis in any form has no wholesome effect on morphologicalabnormalities. Anaemia of CRF persists and despite treatment remain significantly anemic.References
Allan J. E. Anemia of chronic renal failure in Williams
WJ. Beutle H. Erslev AJ. Lietman MA. Haematology
rd ed Singapore Me Grow, Hill. 1986; 417-25.
Hutton R.A. Shea M.IO, Haemostatic mechanism in
Uremia. elm Pathol 1968:21 406-11.
Merrill JP. Hamper’s CL. Uraemia Progress in
pathophysiology and treatment New Yourk: Grune and
Stralton, 1971r 1-47.
Allan. .1 F. Erythropoietin. N Engl J. Med 1991:324:
- 44.
Eschbach JW. Funl D. Adanson .1. Kuin Scribner BH,
finch CA. Erythropoiesis in patients with renal failure
undergoing chronic dialysis. N Engl .1 Med 1967;
:653- 8
Adamson J.W. Exhbach .1. finch CA, The Kidneand
Erythropoiesis, Am .1 Med 1968; 44:725-31
Yawata Y. Howe R. Jacob IIS. Abnormal red cells
metabolism causing haemolysis in uraemia, aim intern
Med 1973; 79:362-7.
Dacie’s JV, Lewis SM Practical haematology. 6lh ed.
Edinburgh Churchill Livingstone 1984, 1-13.
Dacie’s. IV. Lewis SM. Practical haematology. 6lh ed.
Edinburgh Churchill Livingstone 1984; 22-49.
Dacie’s JV, Lewis SM. Practical haematology. 6"' ed
Edinburgh: Churchill Livingstone; 1984; 50-61
Huraib-S, Gader-AM; al-Momen-AK; Abu-Aisha-H;
al- Wakeel-J: Memon. N.A. One-year experience of
very low' doses of subcutaneous erythropoietin in
continuous ambulatory peritoneal dialysis and its effect
on haemostasis. Haemostasis. 1995:25(6) 299-304.
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.
