IN-HOSPITAL OUTCOME OF ACUTE MYOCARDIAL INFARCTION IN CORRELATION WITH ‘THROMBOLYSIS IN MYOCARDIAL INFARCTION’ RISK SCORE

Authors

  • Arslan Masood
  • Moazzam Ali Naqvi
  • Shariq Sohail Jafar
  • Akif Ali Mufti
  • Zubair Akram

Abstract

Background: Effective risk stratification is integral to management of acute coronary syndromes(ACS). The Thrombolysis in Myocardial Infarction (TIMI) risk score for ST-segment elevationmyocardial infarction (STEMI) is a simple integer score based on 8 high-risk parameters that canbe used at the bedside for risk stratification of patients at presentation with STEMI. Objectives:To evaluate the prognostic significance of TIMI risk score in a local population group of acuteSTEMI. Material and Methods: The study included 160 cases of STEMI eligible forthrombolysis. TIMI risk score was calculated for each case at the time of presentation and werethen followed during their hospital stay for the occurrence of electrical and mechanicalcomplications as well as mortality. The patients were divided into three risk groups, namely ‘lowrisk’, ‘moderate-risk’ and ‘high-risk’ based on their TIMI scores (0–4 low-risk, 5–8 moderate-risk,9–14 high risk). The frequencies of complications and deaths were compared among the three riskgroups. Results: Post MI arrhythmias were noted in 2.2%, 16% and 50%; cardiogenic shock in6.7%, 16% and 60%; pulmonary edema in 6.7%, 20% and 80%; mechanical complications of MIin 0%, 8% and 30%; death in 4.4%, 8%, and 60% of patients belonging to low-risk, moderate-riskand high-risk groups respectively. Frequency of complications and death correlated well withTIMI risk score (p=0.001). Conclusion: TIMI risk score correlates well with the frequency ofelectrical or mechanical complications and death after STEMI.Keywords: ST elevation MI, Acute Myocardial infarction, Ischemic heart disease

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Published

2010-12-01