SQUAMOUS CELL CARCINOMA OF THE CONJUNCTIVA: ANALYSIS OF FIFTEEN CASES
AbstractBackground: To document various clinical presentations and management options ofconjunctival squamous cell carcinoma (CSCC) in patients attending ophthalmic out patientsdepartment (OPD) of a tertiary care centre. This case series was carried out in the Department ofOphthalmology Civil Hospital and, Dow University of Health Sciences, Karachi and werereviewed from June 2004 to December 2007. Methods: Socio-demographic data and clinicalfeatures of patients with biopsy proven conjunctival squamous cell carcinoma were recorded andanalysed. All patients underwent complete ophthalmic examination by a fellow ophthalmologistand clinical findings were recorded on a prescribed Performa. Data was analysed in terms offrequency, means and median by SPSS for windows V.15. Results: Seventy-two percent of thepatients were male and 28% were female, more than 80% of patients were in the age group ofseventy years and above. Eighteen percent of patients developed intraocular invasion and the eyeshad to be enucleated. Conclusion: CSCC occurs in sun damaged ocular surface usually at limbus,elderly men are more commonly involve, recurrence is a feature of disease and high risk in olderindividual. In our treatment we used various therapies, excision with clear margin, topicalmitomycin C adjunctive cryotherapy and amniotic graft.Keywords: Conjunctival squamous cell carcinoma, elderly men, clinical presentations, recurrence,management options
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