RESISTANCE PATTERNS OF URINARY ISOLATES IN A TERTIARY INDIAN HOSPITAL

Authors

  • Azra S. Hasan
  • D. Nair
  • J Kaur
  • G. Baweja
  • M Deb
  • P. Aggarwal

Abstract

Background: To analyze the pathogenic organisms recovered from patients with urinary tractinfection in a tertiary Indian hospital setting along with determination of the occurrence and antimicrobial sensitivity of uropathogens on a retrospective basis during a period of one year.Methods : A total of 5073 urine samples were processed. Urine culture was done usingconventional microbiological techniques. Biochemical testing was used to identify the organismsand antibiotic sensitivity was done by the Kirby Bauer method. Results: A total of 2436uropathogens were isolated. E coli were seen in 50.7% samples followed by Klebsiella sp(27.6%). Staphylococcus aureus was the commonest Gram- positive isolate (1.5%). Urinary tractinfection (UTI) was seen in 70.5% females as compared to 29.5% males. A high recovery ofisolates was noted from July to September. Multi drug resistance was commonest withEnterococcus (78.8%) followed by Pseudomonas (65.1%). Drugs, which retained usefulness forGram-negative isolates, were amikacin, norfloxacin and cefotaxime. For Gram-positive isolates,vancomycin, teicoplanin, lincomycin and Norfloxacin were very effective. Conclusions: Ourstudy highlights the changing etiology of UTI and emergence of drug resistance within the Indiansubcontinent.Keywords: Urinary Tract Infections, Pathogens, Antibiotics

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Published

2007-03-01

Issue

Vol. 19 No. 1 (2007): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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