IRON DEFICIENCY ANAEMIA IN MODERATE TO SEVERELY ANAEMIC PATIENTS
Abstract
Background: Anaemia is defined as a clinical abnormality characterized by reduction inhaemoglobin concentration below the normal for age, sex, physiological condition and altitudefrom the sea level of a person. It can be of different types, the commonest being iron deficiencyanaemia which affects mostly pregnant and lactating females and growing children in thedeveloping world. The present study was conducted at Ayub Teaching Hospital on this problem ofglobal importance. Methods: One hundred consecutive anaemic patients were selected from AyubTeaching Hospital. After detailed history and examination, preliminary blood tests including fullblood counts, platelets count, retics count, absolute blood values and blood film examination (alltests done by visual method) were done in the laboratories of Ayub Teaching Hospital and AyubMedical College, Abbottabad. A clinical diagnosis was made based upon the findings of history,examination and blood tests. In patients suspected to have iron deficiency anaemia, serum ironstudies (i.e. serum iron, Total iron binding capacity (TIBC) and serum ferritin) were done toconfirm the diagnosis. Results: Sixty eight patients were found to have iron deficiency anaemia.Females were affected more than the males. Female to male ratio being 1:5:1. Majority of thepatients (82.2%) were aged 21-60 years. However, there were two peaks (21% & 25%) in agegroups 21-30 and 41-50 respectively. Based upon serum ferritin concentrations, most of thepatients were found to suffer from moderate iron deficiency anaemia (53%).Conclusion: Irondeficiency anaemia is the commonest type of anaemia in our area. It is more common in females.It is more common in age group 21-60 years, with two peaks, one in 21-30 years and the other in41-50 years.Key Words: Anemia, Iron deficiency, FerritinReferences
Viteri Fe. A new concept in the control of iron deficiency:
Community based preventive supplementation of at-risk
groups by weekly intake of iron supplements. Biomed
Environ Sci 1998;11(1):46-60.
Cook JD. Iron deficiency anaemia. Baillieres Clin Haematol
;7:787-804.
Wintrobe’s clinical haematology 9th edition. Etiological
factors in iron deficiency. Philadelphia: Lea & Febiger;1993.
Weissinger F. Basic principals and clinical significance of
iron-deficiency. Fortsch Med 1999;115(31):35-38.
Jackson J. The angiographic diagnosis of colonic carcinoma.
Clin Radiol 1998;53(5):345-49.
Sakiewiez P, Pagarini E. The use of iron in patients on
chronic dialysis: mistake and misconceptions. J Nephrol
;11(1):5-15.
Iron deficiency. Bulletin of the World Health Organization,
; 76(Suppl-2):121-123.
Hayat TK. Iron deficiency anaemia during pregnancy. J Coll
Physicians Surg Pak 1997;7(1):11-13.
Syed TS. Iron deficiency anaemia in pregnant women
attending the antenatal clinic. Medical Channel 1998;3(3):49-
Akhter MS, Akhter MW, Tajammul A, Malik M, Nighat U,
Akhtar NS. Profile of anaemic patients attending a tertiary
care hospital in Pakistan, study of 650 cases. Medical
Channel 1997;3(2):9-12.
Hassan K, Ikram N, Shafi MS, Akhtar MJ. Iron deficiency
anaemia – Bone marrow aspiration vs serum iron, TIBC &
transferring saturation. Specialist 1994;10(2):145-50.
Schmaurrer-B. Laboratory diagnosis in iron deficiency
anaemia. Fortschr Med 1997;115(31):32,34-35.
Smieja MJ, Cook DJ, Hunt DL, Ali MA, Guyalt GH.
Recognizing and investigating iron deficiency anemia in
hospitalized elderly people. Can Med Assoc J
;155(5):691-6.
Khan IA. A study of anaemia in NWFP. Khyber Medical
journal 1988;6(1-2):34-40
Paracha PI, Hameed A, Simon J, Jamil A, Nawab G.
Prevalence of anemia in semiurban areas of Peshawar,
Pakistan: A challenge for health professionals and policy
makers. J Pak Med Assoc 1997;47(2):49-53
Karim SA, Khurshid M, Memon AM, Jafarey SN. Anemia in
pregnancy – Its cause in the underprivileged class of Karachi.
J Pak Med Assoc 1994;44(4):90-91.
Hashmi JA, Afroz N, Nisa Q, Malik F, Saeed M, Choudhry
AS. Study of anemia in pregnancy at the Jinnah postgraduate
Medical Center, Karachi. J Pak Med Assoc 1973;12(3):23-
Heiner JD, Siddiqui AR, Aziz MA. Anemia in pregnancy in
an urban population of West Pakistan. Pak J Med Res 1972;
(1);26-35
Baig L, Thaver I, Haq IU, Iqbal R. risk factors associated
with anemia in children six months to five years of age
residing in a squatter settlement of Karachi. Pak J Med Res
;35(4)176-8.
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.