EPIDEMIOLOGICAL ASPECTS OF ALLERGIC CONJUNCTIVITIS: A CROSS SECTIONAL STUDY

Authors

  • Ayisha Kausar shifa college of medicine , Islamabad.shifa international hospital Islamabad.
  • Nadia Akhtar Federal Medical & Dental College. Federal General Hospital, Islamabad.
  • Nighat Akbar Allergy Centre, National Institute of Health, Islamabad.

DOI:

https://doi.org/10.55519/JAMC-01-9432

Keywords:

Ocular allergy, Allergic conjunctivitis, Vernal keratoconjunctivitis, Epidemiology, Conjunctivitis

Abstract

Background: Allergic conjunctivitis is a common ocular disease which not only affects vision but can also compromise the quality of life of patients to a greater extent. If it is not properly managed it can lead to decreased vision due to corneal complications. This study was conducted to evaluate the epidemiological aspects of allergic conjunctivitis. Methods: This cross-sectional study was carried out in the Ophthalmology department of Federal General Hospital, from June 2018 to June 2020. We enrolled 236 patients of allergic conjunctivitis. Data collection form consisted of a structured questionnaire, records of ocular findings using slit lamp biomicroscope and skin prick test results. Data analysis was done using SPSS version 23.0. Results: The mean age (±SD) of study population was 22.71±13.11 years, 60.2% were females. Most common type of conjunctivitis was vernal keratoconjunctivitis (VKC) 46.2%, followed by perennial (27.1%), seasonal (17.4%) and atopic (9.3%). There was significant association of type of conjunctivitis with the age, p-value<0.001. VKC was prevalent in patients of age <20 years. There was a significant association of gender with type of conjunctivitis, p-value =0.000. Perennial variety was more prevalent in females while VKC was common in males. Collateral atopy was present in 52.1% patients. Corneal involvement was seen in 17.8% patients. There was a significant association between corneal involvement and interference with daily visual activities, p-value 0.034. SPT was positive in 79.7% patients. Conclusion: Ocular allergies/ conjunctivitis was more prevalent in female population. VKC is the most common type of allergic conjunctivitis, prevalent in males of age <20 yrs. Allergic rhinitis was the most common co-morbidity followed by dermatitis.

Author Biographies

Ayisha Kausar, shifa college of medicine , Islamabad.shifa international hospital Islamabad.

Associate Professor, Ophthalmology.

Nadia Akhtar, Federal Medical & Dental College. Federal General Hospital, Islamabad.

Assistant Professor of Ophthalmology, Federal Medical & Dental College. Associate Eye Surgeon, Federal General Hospital, Islamabad.

Nighat Akbar, Allergy Centre, National Institute of Health, Islamabad.

Consultant Allergist, Allergy Centre, National Institute of Health, Islamabad.

References

Arif AS, Aaqil B, Siddiqui A, Nazneen Z, Farooq U. Corneal Complications And Visual Impairment In Vernal Keratoconjunctivitis Patients. J Ayub Med Coll Abbottabad 2017;29(1):58–60.

Bielory L, Delgado L, Katelaris CH, Leonardi A, Rosario N, Vichyanoud P. ICON: Diagnosis and management of allergic conjunctivitis. Ann Allergy Asthma Immunol 2020;124(2):118–34.

Thong BY. Allergic conjunctivitis in Asia. Asia Pac Allergy 2017;7(2):57–64.

Baig R, Ali AW, Ali T, Ali A, Shah MN, Sarfaraz A, et al. Prevalence of allergic conjunctivitis in school children of Karachi. J Pak Med Assoc 2010;60(5):371–3.

Leonardi A, Doan S, Fauquert JL, Bozkurt B, Allegri P, Marmouz F, et al. Diagnostic tools in ocular allergy. Allergy 2017;72(10):1485–98.

Kang SY, Song WJ, Cho SH, Chang YS. Time trends of the prevalence of allergic diseases in Korea: A systematic literature review. Asia Pac Allergy 2018;8(1):e8.

Miyazaki D, Fukagawa K, Okamoto S, Fukushima A, Uchio E, Ebihara N, et al. Epidemiological aspects of allergic conjunctivitis. Allergol Int 2020;69(4):487–95.

Mpairwe H, Nkurunungi G, Tumwesige P, Akurut H, Namutebi M, Nambuya I, et al. Risk factors associated with rhinitis, allergic conjunctivitis and eczema among schoolchildren in Uganda. Clin Exp Allergy 2021;51(1):108–19.

Singh S, Sharma BB, Salvi S, Chhatwal J, Jain KC, Kumar L, et al. Allergic rhinitis, rhinoconjunctivitis, and eczema: prevalence and associated factors in children. Clin Respir J 2018;12(2):547–56.

Dupuis P, Prokopich CL, Hynes A, Kim H. A contemporary look at allergic conjunctivitis. Allergy Asthma Clin Immunol 2020;16:5.

Abo-Ali FH, Farres MN, Shahin RY, Eissa AM, Ahmed A, Abdel-Monsef A, et al. Skin Prick Test Reactivity to Aeroallergens among Egyptian Patients with Isolated Allergic Conjunctival Disease. Egypt J Immunol 2015;22(2):41–7.

Leonardi A, Castegnaro A, Valerio AL, Lazzarini D. Epidemiology of allergic conjunctivitis: clinical appearance and treatment patterns in a population-based study. Curr Opin Allergy Clin Immunol 2015;15(5):482–8.

Jongvanitpak R, Vichyanond P, Jirapongsananuruk O, Visitsunthorn N, Pacharn P. Clinical characteristics and outcomes of ocular allergy in Thai children. Asian Pac J Allergy Immunol 2020;2020:1–7.

Leonardi A, Piliego F, Castegnaro A, Lazzarini D, La Gloria Valerio A, Mattana P, et al. Allergic conjunctivitis: a cross-sectional study. Clin Exp Allergy 2015;45(6):1118–25.

Hayilu D, Legesse K, Lakachew N, Asferaw M. Prevalence and associated factors of vernal keratoconjunctivitis among children in Gondar city, Northwest Ethiopia. BMC Ophthalmol 2016;16(1):167.

Feng Y, Wang X, Wang F, Liu R, Chen L, Wu S, et al. The Prevalence of Ocular Allergy and Comorbidities in Chinese School Children in Shanghai. Biomed Res Int 2017;2017:7190987.

Alqurashi KA, Bamahfouz AY, Almasoudi BM. Prevalence and causative agents of allergic conjunctivitis and its determinants in adult citizens of Western Saudi Arabia: A survey. Oman J Ophthalmol 2020;13(1):29–33.

Shokouhi Shoormasti R, Pourpak Z, Fazlollahi MR, Kazemnejad A, Nadali F, Ebadi Z, et al. The Prevalence of Allergic Rhinitis, Allergic Conjunctivitis, Atopic Dermatitis and Asthma among Adults of Tehran. Iran J Public Health 2018;47(11):1749–55.

Kim Y, Oh I, Lee J, Sim CS, Oh YS, Lee JH. Astigmatism Associated with Allergic Conjunctivitis in Urban School Children. J Ophthalmol 2019;2019:9453872.

Ahmed A, Minhas K, Micheal S, Ahmad F. Prevalence of skin test reactivity to aeroallergens in the Pakistani population. Public Health 2011;125(5):324–6.

Published

2022-01-01