Farhat Deeba, Bushra Khan, Samina Naseem Khattak


Background: Ectopic pregnancy is a common life-threatening emergency in the developing world. It is
a cause of maternal morbidity and mortality in the first trimester and these mortalities can be reduced if
it is properly managed. The objective of this study was to assess the variable clinical presentations and
outcome of treatment of ectopic pregnancy in Ayub Teaching Hospital Abbottabad. Methods: Two
hundred and fifty-five patients with ectopic pregnancy managed in Ayub Teaching Hospital over period
of 10 years, were included in the study. The clinical presentation, diagnostic modalities and out come of
treatment were recorded and analysed. Results: Out of 255 patients 43 (16.86%) had un-ruptured tubal
pregnancy, 183 (71.76%) had ruptured ectopic pregnancy and 22 (8.62%) had chronic ectopic
pregnancy. At laparotomy, salpingectomy was done in 229 (89.80%) patients, salpingo-ophrectomy in
2 patients (0.78%), linear salpingostomy in 15 (5.88%) patients. Medical treatment was given to 5
patients and 8 patients were treated conservatively. There was no maternal mortality. Conclusion: In
spite of various recent advances in the management of ectopic pregnancy, conventional surgical
treatment by laparotomy is still the most widely used modality of treatment in our institution. With
appropriate and prompt management, maternal mortality due to ectopic pregnancy can be prevented.
Keywords: Ectopic pregnancy, conventional surgical management, laparotomy, salpingectomy

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Boyer J, Coste J, Fernandez H, Pouly JL, Job-Spira N. Sites of

ectopic pregnancy: a 10 year population-based study of 1800

cases. Hum Reprod 2002;17:3224–30.

Farquhar CM. Ectopic pregnancy. Lancet 2005;366:583–91.

Goldner TE, Lawson HW, Xia Z, Atrash HK. Surveillance for

ectopic pregnancy: United States, 1970–1989. MMWR CDC

Surveill Summ 1993;42(6):73–85.

Menon S, Sammel M, Vichnin M, Barnhart KT. Risk Factors for

Ectopic Pregnancy: A Comparison Between Adults and

Adolescent Women. J Pediatr Adolesc Gynecol 2007;20:181–5.

Piasarska MD, Carson SA. Incidence and risk factors for ectopic

pregnancy. Clin Obstet Gynecol 1999;42:2–8.

Barnhart KT, Sammel MD, Gracia CR, Chittams J, Hummel

AC, Shaunik A, et al. Risk factors for ectopic pregnancy in

women with symptomatic first trimester pregnancies. Fertil Steril


Condous G. Lu, Van Huffel SV, Timmerman D, Bourne T.

Human chorionic gonadotrophin and progesterone level is in

pregnancies of unknown location. Int J Obstet Gynaecol


Kadar N, Bohrer M, Kemmann E, Shelden R. The discriminatory

human chorionic gonadotropin zone for endovaginal sonography:

a prospective, randomized study. Fertil Steril 1994;61:1016–20.

Khaleeque F, Sidiqui RI, Jafarey SN. Ectopic pregnancy: a three

year study. J Pak Med Assoc 2001;51:240–3.

Shoaib F. Ectopic pregnancy. A study of 50 cases. J Coll

Physicians Surg Pak 1994;4(2):65–70.

J Ayub Med Coll Abbottabad 2012;24(3-4) 81

Amoko DH, Buga GA. Clinical Presentation of Ectopic

Pregnancy in Transkei, South Africa. East Afr Med J


Sherman D, Langer R, Sadovsky G, Bukovsky I, Caspi E.

Improved fertility following ectopic pregnancy. Fertil Steril


Gracia CR, Barnhan KT. Diagnosing ectopic pregnancy: decision

analysis comparing six strategies. Obstet Gynecol 2001;97:469–

Gazvani MR. Modern Management of Ectopic Pregnancy. Br J

Hosp Med 1996;56:597–9.

Barnhart KT. Ectopic Pregnancy. N Eng J Med 2009;361:379–

Shrestha J, Saha R. Comparison of laparoscopy and laparotomy

in the surgical management of ectopic pregnancy. J Coll

Physicians Surg Pak 2012;22:760–4.

Yakasai IA, Abdullahi J, Abubakar I. Management of ectopic

pregnancy in Aminu Kano Teaching Hospital Kano Nigeria: A 3-

year. Global Adv Res J Med Med Sci 2012;1(7):181–5.

Bhatla N (Ed). Jeffcoate’s Principles of Gynaecology. New

Delhi: Arnold; 2001.p. 208–24.

Ekici E, Yapar EG, Gökmen O, Danişman N, Ozmen S. Ectopic

pregnancy: transvaginal sonographic findings of 152 cases.

Ultrasound Obstet Gynecol 1993;3:271–5.

Pouly JL. Strategy for treatment of ectopic pregnancy:

conservative treatment. In: Sutton C, Diamond MP (Eds).

Endoscopic surgery for gynaecologists, 2nd ed. London: WB

Saunders; 1998.p. 150–7.

Dubuisson JB, Aubriot FX, Cardone V. Laparoscopic

salpingectomy for tubal pregnancy. Fertil Steril 1987;47:225–8.

Feichtinger W, Kemeter P. Conservative treatment of ectopic

pregnancy by transvaginal aspiration under sonographic control

and methotrexate injection. Lancet 1987;1(8529):381–2.

Gordon AG, Lewis BV, Decherney AH (Eds). Atlas of

Gynecologic endoscopy 2nd ed. London: Mosby-Wolfe; 1995.p.


Sy Sy T, Diallo Y, Toure A, Diallo FB, Balde AA, Hyjazi Y, et

al. Management of ectopic pregnancy in Conkry, Guinea. Med

Trop (MARS) 2009;69:565–8.

Sowter M, Frappell J. The role of laparoscopy in the

management of ectopic pregnancy. Rev Gynaecol Practice


Saraj A, Wilcox J, Najmabadi S, Stein S, Johnson M, Paulson R.

Resolution of hormonal markers of ectopic gestation: a

randomized trial comparing single-dose intramuscular

methotrexate with salpingostomy. Obstet Gynecol 1998;92:989–

Sowter M, Farquhar C, Petrie K, Gudex G. A randomized trial

comparing single dose systemic methotrexate and laparoscopic

surgery for the treatment of unruptured tubal pregnancy. Br J

Obstet Gynaecol 2001;108:192–203.

Lipscomb G, Bran D, McCord M, Portera J, Ling F. Analysis of

three hundred fifteen ectopic pregnancies treated with single-dose

methotrexate. Am J Obstet Gynecol 1998;178:1354–8.

Lipscomb G, McCord M, Stovall T, Huff G, Portera S, Ling F.

Predictors of success of methotrexate treatment in women with

tubal ectopic pregnancies. N Engl J Med 1999;341:1974–8.


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