COMPARATIVE ANALYSIS OF TYPE OF MYOCARDIAL INFARCTION IN PATIENTS WITH SUCCESSFUL OR UNSUCCESSFUL STREPTOKINASE THROMBOLYSIS FOLLOWING ST ELEVATION MYOCARDIAL INFARCTION

Sher Bahadar Khan, Rafiullah Rafiullah, Lubna Noor, Khurshid Ahmad, Yasir Adnan, Amber Ashraf, Asif Iqbal, Hafiz ur Rehman, Mohammad Hafizullah

Abstract


Objective: To study the effect of thrombolytic therapy in term of success and failure on the type of ST
elevation MI, using streptokinase. Material and Methods: This was a comparative study, conducted at
Department of Cardiology, Lady Reading Hospital, Peshawar, from October 2006 to October 2007.
Patients with first acute myocardial infarction were divided into group A (successful thrombolysis) and
group B (unsuccessful thrombolysis) using ECG criteria. Results: Total number of patients were 200.
Group A included 136 (68%) patients and group B included 64 (32%) patients. There were total 88
(44%) patients of anterior MI with 47 patients in group A and 41 patients in group B (34.6% vs 64.0%,
p<0.001). There were total 110 (55.0%) patients of inferior MI with 88 patients in group A and 22
patients in group B (64.7% vs 34.4%, p<0.001). Lateral myocardial infarction was diagnosed in 2 (1%)
patients with 1 patient each in group A and group B (0.7% vs 1.6%, p=0.583). Conclusion: Anterior
MI was associated with a higher rate of thromblysis failure while inferior MI and lateral wall MI was
associated with a higher rate of successful thrombolysis.
Keywords: Myocardial infarction; thrombolysis; type of myocardial infarction

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