CLINICAL PRESENTATIONS IN IMMUNE THROMBOCYTOPENIC PURPURA

Jamila Farid, Nasreen Gul, Waqar -Ur-Rehman Qureshi, Muhammad Idris

Abstract


Background: Thrombocytopenia is an important cause of mucocutanaeous bleeding in adult and
paediatric patients. Immune thrombocytopenia is one of the common causes of thrombocytopenia. Its
clinical presentations vary from patient to patient, not studied in our area previously. The present
study was planned to see the frequency of clinical presentations of Immune Thrombocytopenic
Purpura (ITP) in our patients. Methods: This prospective study was conducted on 125 patients with
ITP, diagnosed by exclusion of secondary causes of thrombocytopenia. Bone marrow examination
was performed on all the patients. Results: Bruising, epistaxis and gum bleeding were the
commonest clinical presentations in adults and children. Bleeding was more severe in acute cases.
Increased menstrual bleeding was seen in female patients. Conclusion: Bruising, epistaxis and gum
bleeding are the commonest clinical presentations of ITP. Our results are not much different from
those of the other studies conducted in Pakistan.
Keywords: Thrombocytopenia, Immune thrombocytopenic purpura, mucocutanaeous bleeding

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