CLINICAL CHARACTERISTICS OF PATIENTS WITH DENGUE FEVER: REPORT OF 48 PATIENTS IN 2010

Atiya Mahboob, Zafar Iqbal, Rabil Javed, Azeem Taj, Asma Munir, Munir Akhtar Saleemi

Abstract


Background: Dengue fever is a mosquito born viral disease. It occurs in tropical and sub-tropical areas
of the world. Symptoms appear 3−14 days after the infective bite. Mortality can occur in dengue
hemorrhagic fever and dengue shock syndrome unless prompt and adequate management is provided.
Objective: To determine the clinical and epidemiological characteristics along with outcome of
patients with dengue fever (DF) dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).
Design: Prospective, follow-up study. Place and duration of study: Department of Medicine, Shaikh
Zayed Federal Postgraduate Medical Institute, Lahore from 3rd Oct 2010 to 20th Nov 2010. Patients
and Methods: Specific serological tests for dengue fever were done in all 60 patients admitted with
suspected diagnosis of DF, DHF and DSS. Forty-eight confirmed cases were evaluated for age, gender,
clinical features and outcome of the disease. Results: Forty-eight out of 60 patients had positive
serology for dengue fever. Male to female ratio was 1.09:1. Their ages ranged from 5 years to 68 years
with the mean of 31.5±15.2 years. DF, DHF and DSS were found in 71%, 19% and 10% cases
respectively. Common presentations were fever (100%), skin rash (83.33%), myalgia (69.75%),
restlessness (66.67%) and rigors and chills (66.67%). All, except one patient improved clinically. One
patient died on second day of admission. Conclusion: Dengue fever, a viral infection is re-emerging as
a serious public health problem. Fever, rash, myalgia with rigors and chills were common presenting
features.
Keywords: Dengue fever, Dengue hemorrhagic fever, dengue shock syndrome, skin rash, epidemic

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