Ghayyur Khan, Nasir Khan, Abdul Aziz


Background: Diabetes is a metabolic disorder that affects many systems in the body. Cerebral
atrophy is one of the complications of diabetes and research is on going to find out its
aetiopathological factors. The main aim of the study was to determine the frequency of cerebral
atrophy in type-II diabetes mellitus using magnetic resonance imaging of the brain. Methods: One
hundred diabetic patients (Random blood sugar >126 mg/dl) were recruited in this study after the
informed consent from every patient. Duration of diabetes was five years and more in all the patients
as determined by their glycosylated haemoglobin which was >6 in all the patients. All the patients
were undergone MRI of brain using 1.5 Tesla power magnetic resonance imaging machine of Picker
Company. Evan’s index, a specific parameter for measurement of cerebral atrophy was calculated on
MR images and was used in this study. Results: In male group the frequency of cerebral atrophy was
22 (47%) and in female group it was found to be 23 (43%). When we study the overall population
the frequency was found to be 45 (45%). The results are well in concordance with the previous data
published on this issue. Conclusions: Cerebral atrophy, a complication of long standing diabetes is
quite frequent in our population and is well diagnosed by MRI.
Keywords: Diabetes Mellitus, cerebral atrophy, MRI, frequency, complications of diabetes

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