IMPACT OF RENAL TRANSPLANTATION ON ERECTILE DYSFUNCTION DUE TO CHRONIC RENAL FAILURE IN MALE PATIENTS

Authors

  • Mumtaz Ahmad
  • Qazi Rafiuddin
  • Usman Hassan
  • Ashfaq Ahmad
  • Sajjad Husain

Abstract

Background: Erectile dysfunction can be defined as the persistent inability of man to achieve penileerection and maintain it sufficient for satisfactory coitus. The objectives of this study were to find outthe impact of successful renal transplantation on the degree and frequency of erectile dysfunction.Methods: Thirty patients of end stage renal disease that were on regular haemodialysis and candidatesof renal transplantation of age range 20–55 years were included in the study after getting informedconsent. Erectile functions were assessed by history, examination, investigations and internationalindex of erectile function (IIEF) before and 3 and 6 months after renal transplantation, otherinformation regarding disease and patient were collected in the performa. Results: Out of thirty patients14 (46.6%) patients had sever erectile dysfunction while 16 (53.3%) patients had moderate erectiledysfunction in the pre renal transplantation period. After three months of renal transplantation 15 (50%)had severe erectile dysfunction, 6 (20%) patients moderate erectile dysfunction and 9 (30%) patientsmild erectile dysfunction. After six months 11 (36.6%), 10 (33.3%) and 8 (26.6%) patients had severe,moderate and mild erectile dysfunction respectively. Conclusion: There was improvement in 40%, nochange in 53.3% and deterioration in 6.6% patients in the erectile functions after getting renaltransplantation for end stage renal disease.Keywords: Erectile Dysfunction, End-stage Renal Disease, International Index of ErectileFunction, IIEF

References

Barrou B, Cuzin B, Malavaud B, Petit J, Pariente JL, Buchler M,

et al. Early experience with Sildenafil for the treatment of erectile

dysfunction in renal transplant recipients. Nephrol Dial

Transplant 2003;18:411–7.

Abdel- Hameed IA. Mechanism of vasculogenic erectile

dysfunction after kidney transplantation. BJU Int.2004;94:497–500.

Ayub W, Fletcher S. End-stage renal disease and erectile

dysfunction. Is there any hope? Nephrol Dial Transplant

;15:1525–8.

Carson CC, Patel MP. The epidemiology, anatomy, physiology,

and treatment of erectile dysfunction in chronic renal failure

patients. Adv Rev Replace Ther 1999;6:296–309.

Lue TF. Physiology of penile erection and pathophysiology of

erectile dysfunction and priapism. In: Walsh PC, Retik AB,

Vaughan Jr ED, Wein AJ editors. Campbell’s Urology.8th ed.

Philadelphia: WB Saunders Co, 1998; p.1157–79.

Rhoden EL, Teloken C, Sogari PR, Vargas Souto CA. The use of

the simplified International Index of Erectile Function (IIEF-5) as

a diagnostic tool to study the prevalence of erectile dysfunction.

Int J Impot Res 2002;14:245–50.

Arslan D , Aslan G, Sifil A, Cavdar C, Celebi I, Gamsari T, et al.

Sexual dysfunction in male patients on HD : assessment with the

International Index of Erectile Function (IIEF). Int J Impot Res

;14:539–42.

Zamd M, Gharibi MB, Ramadni B Zaid D. Sexual dysfunction in

male patients under going HD in Morocco. Saudi J. Kidney Dis

Transplant 2005;16:33–9.

Ali ME, Abdel-Hafez HZ, Mahran AM, Mohamed HZ,

Mohamed ER, El-Shazly AM, et al. Erecrile dysfunction in

chronic renal failure patients under going HD in Egypt. Int J

Impot Res 2005;17:180–5.

Musone D, Cindolo L, Altieri V, Russo D. Erectile dysfunction

in kidney transplanted patients. Minerva Urol Nefrol

;55:193–7.

El- Bahnasawy MS, El- Assmy A, El-Sawy E, Ali-El Dein B, ElDein ABS, Rafaie A et al. Critical evaluation of the factors

influencing erectile function after renal transplantation. Int J

Impot Res 2004;16:521–6 .

Burgos FJ, Pascual J, GomezV, Orofino L, Liano F, Ortuno J.

Effect of kidney transplantation and cyclosporine treatment on

male sexual performance and hormonal profile: A Prospective

study. Transplant Proc1997;29:227–8.

Published

2009-03-01

Most read articles by the same author(s)

1 2 > >>