YIELD OF ABRAMS NEEDLE PLEURAL BIOPSY IN EXUDATIVE PLEURAL EFFUSION

Ihsan ullah, Nisar Khan, Huma Jadoon, Munawar Zaman, Ashfaq Ahmed

Abstract


Background: Pleural effusion is the abnormal collection of fluid in the pleural space resulting from
excessive fluid production or decreased absorption and it is one of the most common clinical conditions
that we come across in pulmonology clinics and in hospitals. The objective of prospective study was to
evaluate the diagnostic role of Abrams Needle Biopsy in Exudative Pleural Effusion Methods: The
study was performed at the Department of Pulmonology, Ayub Teaching Hospital, Abbottabad over a
period of 1 year, i.e., January 2008 to December 2008. Sixty-three patients of either sex and all ages
with exudative pleural effusion, on whom Abrams Needle Biopsy was performed were included in the
study. Minimum of four specimens from each patient were taken and histopathology done. Results:
Out of 63 patients, histopathology revealed the cause in 60 (95%) cases. Tuberculosis, malignancy and
rheumatoid pleurisy were confirmed in 34, 24, and 2 cases respectively. Specimens of 3 patients did not
reveal any result and showed non-specific inflammation and were further investigated accordingly.
Conclusion: The diagnostic yield of Biopsy was 95%. Pleural biopsy is still a reliable and valuable
investigation in diagnosing pleural effusion, provided that adequate pleural specimen is taken.
Keywords: Pleural biopsy, Exudative pleural effusion, malignant pleural effusion, Tuberculosis

References


Diaz-Guzman E, Dweik RA. Diagnosis and management of

pleural effusions: a practical approach. Compr

Ther 2007;33(4):237–46.

Marel M, Zrustova M, Stasny B, Light RW. The incidence of

pleural effusion in a well-defined region. Epidemiologic

study in central Bohemia. Chest 1993;104:1486–9.

Light RW, MacGregor MI, Luchsinger PC, Ball WC Jr.

Pleural effusion: The diagnostic separation of transudates and

exudates. Ann Intern Med 1972;77:507–13.

Noble J. Textbook of Primary Care Medicine. 3rd ed. St.

Louis, Mo: Mosby; 2001.p.725.

Heidari B, Bijani K, Eissazadeh M, Heidari P. Exudative

pleural effusion: effectiveness of pleural fluid analysis and

pleural biopsy. East Mediterr Health J. 2007;13:765–73.

Frank W. Current diagnostic approach to pleural effusion.

Pneumologie 2004;58(11):777–90.

Khadadah ME, Muqim AT, Al-Mutairi AD, Nahar IK,

Sharma PN, Behbehani NH, et al. Closed percutaneous

pleural biopsy. A lost art in the new era. Saudi Med J

;30(6):793–7.

Chakrabarti B, Ryland I, Sheard J, Warburton CJ, Earis JE.

The role of Abrams percutaneous pleural biopsy in the

investigation of exudative pleural effusions. Chest.

;129(6):1549–55.

Light RW, Erozan YS, Ball WC Jr. Cells in pleural fluid.

Their value in differential diagnosis. Arch Intern Med

;132:854–60.


Refbacks

  • There are currently no refbacks.


Contact Number: +92-992-382571

email: [jamc] [@] [ayubmed.edu.pk]