EFFECT OF ALLOXAN — INDUCED DIABETES ON SERUM ELECTROLYTES AND LIPIDS IN RABBITS

Muhammad Shafique, Misbahul Ain Khan, Amjad M. Chughtai, Akbar Ali Kahloon, Iqbal Ahmad Khan

Abstract


ABSTRACT:
Effect of alloxan on scrum glucose, electrolytes and lipids was observed in 20 induceddiabetic rabbits. Thirteen days after alloxan administration sufficient hyperglycemia was detected and
the serum levels of magnesium and sodium were lower significantly. Out of 20, eight Rabbits (40%)
developed marked hypomagnesemia and hyponatremia which were inversely associated with the
degree of hyperglycemia. Serum HDL-cholesterol was also decreased and triglycerides increased
statistically. However, the difference in the mean values of total cholesterol, calcium and potassium
were found to be non-significant after alloxan injection.

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