EFFECT OF ANTICONVULSANT DRUGS ON MONOVALENT CATIONS

M. Shafique, M. Ashraf, S.H. Shah, M.U. Ghani

Abstract


ABSTRACT:
Sixty patients receiving anticonvulsant drugs like tegretol 9 Carbamazepine and 61 agematched controls were studied to determine the disturbances in sodium and potassium. levels There
was a significant difference in sodium level the mean serum sodium levels of the subjects (138.8±
0.6 mEq/L) and the controls (141.7± 0.4 mEq/L). Thirteen (21.7%) of the subjects, but none of the
controls, had sodium levels 135 mEq/L. But the mean values of potassium (4.3 ± 0.02 mEq/L), were
not significantly changed as compared to controls. The risk of hyponatremia increased with age
(subjects 30 years old had four limes the prevalence of hyponatremia as those < 30 years old.

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