CO-RELATION OF TOXOPLASMA GONDII INFECTION AND COUSIN MARRIAGES

Authors

  • M. Saqib Lodhi
  • M. Aslam Khan
  • Manzoor Ahmed

Abstract

ABSTRACTSera from 735 women of child-bearing age (15-45) years) were tested for the presence ofIgG antibodies to Toxoplasma gondii by Enzyme-Linked Immunosorbent Assay (ELISA)technique. Along with other information’s, the respondents were also asked about the relationshipof their parents to each other before marriage. 263 (35.78%) women were seropositive forToxoplasma antibodies. Seropositivity was much higher (48.63%) in the group whose parents werefirst cousins and the rate declined progressively in second cousins (41.46%) distant blood relations(26.82%), same caste (26.63%) and different caste (23.73%). This difference is statistically highlysignificant (P<0.005). The reason for high prevalence of Toxoplasma gondii infection amongwomen whose parents arc first cousins is not clear. Further study in this regard is suggested.

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