COFFEE INTAKE AND ELEVATED LIPID PROFILE IN AMI PATIENTS

Authors

  • Muhammad Abdul Rehman
  • Hafiz Hafeez-ul- Haq
  • Muhammad Tayyab
  • Faiz Ahmed Khan

Abstract

Coffee intake from diet records was studied in association with serum lipid profile concentrations in a crosssectional sample of 60 middle aged men and women suffering from acute myocardial infarction to determine the significance and form of their interrelationships. All the subjects were evaluated for diabetes mellitus, nephrotic syndrome and hyper lipid - anemia. Heavy drinking of coffee revealed a highly significant (p <0.001) increase in levels of total cholesterol and LDL-cholesterol. Graphic analysis revealed that serum concentrations of total cholesterol and LDLcholesterol were positively related, which were statistically less significant (p<0.01) to intake of upto 3 cups of coffee per day and more significant (p<0.001) with intake exceeding 3-4 cups. These results suggest that heavy coffee drinking patients of acute myocardial infarction have significant increases in levels of lipoprotein profiles when compared to those faking no coffee.

References

Stamler J. Population studies. In: Ley RI, Ritkind

BM, Dennis BH & Ernst N (Eds). Nutrition, lipid

and coronary heart disease: a global view. Raven

Press. New York, 1979, pp 25-88.

Heiss G, Johnson NJ, Reiland S, Davis CE &

Tyroler HA. The epidemiology of plasma high

density lipoprotein cholesterol levels. The Lipid

Research Clinics Program Prevalence Study.

Circulation, 1980; 62: Suppl IV: 116- 36.

Knuiman JT, Hermus RJJ & Hautvast JGAJ.

Serum total and high density lipoprotein (HDL)

cholesterol concentrations in rural and urban boys

from 16 countries. Atherosclerosis, 1980; 36: 529-

Knuiman JT & West CE. HDL-cholesterol in men

from thirteen countries. Lancet, 1981; 2: 367-8.

Thompson GR. Dietary and pharmacological

control of lipoprotein metabolism. In: Miller NE

& Lewis B. (Eds). Metabolic aspects of

cardiovascular disease. Vol 1. Elsevier Press,

Amsterdam, 1981; pp 59-75.

Mattson FT, Erickson BA & Kligman AM. Effect

of dietary cholesterol on serum cholesterol in man.

Am J Clin Nutr. 1972; 25: 589-94.

Keys A & Parlin RW. Serum cholesterol response

to changes in dietary lipids. Am J Clin Nutr, 1966;

: 175-81.

Hegsted DM, McGandy RB, Myers ML & Stare

FT. Quantitative effects of dietary fats on serum

cholesterol in man. Am J Clin Nutr, 1965; 17: 281-

Arab L, Kohlmeer M, Schlierf G & Schettler G.

Coffee and cholesterol. N Engl J Med, 1983; 309:

Bejelk E. Colon cancer and blood cholesterol.

Lancet, 1974; i: 1116-17.

Little JA, Shanoff HM, Csima A & Yano R.

Coffee and serum lipids in coronary heart disease.

Lancet, 1966; i: 732-34.

Fried RE, Levine PM. Kwiterorich PO, et al. The

effects of filtered coffee consumption on plasma

lipid levels. Results of a randomized clinical trial.

JAMA, 1992; 267: 811-15.

Shirlow M & Mathers C. Coffee and cholesterol.

N Engl J Med, 1983; 309: 1250.

Thelle DS, Arnesen E & Ford OH. The Tromso

heart study: Does coffee raise serum cholesterol?

N Engl J Med, 1983; 308: 1451- 57.

Kovar MG, Falwood R & Feinleih M. Coffee and

cholesterol. N Engl J Med, 1983; 309: 1249.

Dawber TR, Kannel WB & Gordon T. Coffee and

cardiovascular disease: Observations from the

Framingham study. N Engl J Med, 1974; 291: 871-

Bonaa K. Amesen E, Thelle DS & Forde OH.

Coffee and cholesterol: Is it all in the brewing?

The Tromso study. Br Med J, 1988; 297: 1103-04.

Amesen E, Ford OH & Thelle DS. Coffee and

serum cholesterol. Br Med J, 1984; 288: 1960.

Forde OH, Knursen SF, Amesen E & Thelle DS.

The Tromso Heart Study: Coffee consumption and

serum lipid concentrations in men with

hypercholesterolemia: a randomized intervention

study. Br Med J, 1985; 290: 893- 95.

Aro A, Tuomilehto J, Kostiainen E, Uusitalo U &

Pietinen P. Boiled coffee increases serum low

density lipoprotein concentration. Metabolism,

; 36: 1027-30.

Bak AAA & Grobbee DE. The effect on serum

cholesterol level of coffee brewed by filtering or

boiling. N Engl J Med, 1989; 321: 1432-37.

Superko HR, Bortz WM, Albers JJ & Wood PD.

Lipoprotein and apolipoprotein changes during a

controlled trial of caffeinated and decaffeinated

coffee drinking in man. Circulation, 1989; 80,

Suppl 11: 86.

Zock PI, Katan MB, Merkus MP, Dusseldorp MV

& Hapryvan JL. Effect of lipid rich fraction from

boiled coffee on serum cholesterol. Lancet, 1990;

: 1235-37.

Heiss G & Tyroler HA. Are apolipoprotein useh.il

for evaluating ischemic heart disease? A brief

overview of the literature, In: Lippel K (Ed.):

Proceedings of the Workshop on Apolipoprotein

quantification. Publication 83-1266, Bethesda,

Md., National Institute of Health, 1983, pp 7-22.

Kauftnann NA, Friedlander Y, Halfon ST, et al.

Nutrient intake in Jerusalem: consumption in

adults. Isr J Med Sci, 1982; 18: 1183-97.

Kaufmann NA, Friedlander Y, Halfon ST, et al.

Nutrient intake in Jerusalem: consumption in 17

years old. Isr J Med Sci, 1982; 18: 1167-8.

National Heart, Lung and Blood Institute. Manual

of laboratory' operation. Lipid Research Clinic

Programme, Vol. 1. Lipid and lipoprotein

analysis. Bethesda, Maryland. National Institute

of Health. Publication no (NIH) 75-628, (DHEW),

Richmond W. Preparation and properties of a

cholesterol oxidase from nocardia and its

application to the enzymatic assay of total

cholesterol in serum. Clin Chem, 1973; 19: 1350-

Burstein M & Scholnick HR. Lipoproteinpolyamine-metal

interaction. Adv Lipid Res,

; 2: 67-108.

Friedewald WT, Levy RI & Frederickson DS.

Estimation of low density lipoprotein cholesterol

in plasma without the use of preparative

ultracentrifugation. Clin Chem, 1972; 18: 499-

Hatch FT. Practical methods for plasma

lipoprotein analysis. Adv Lipid Res, 1968: 6: 1-68.

Fossati P & Prencipe L. Clin Chem, 1982; 28:

In: Varley’s Practical Clinical Biochemistry,

by Gowenlock AH, McMurray JR &

MacLauchlan DM. (6th ed.), Heinemann Medical

Books, London, 1988; 464-66.

Zollner N& Kirsch K. Determination of total

lipids. Ges Expt Med, 1962; 135: 545.

Sacks FM, Castelli WP, Donnor A & Kass EH.

Plasma lipids and lipoproteins in vegetarians and

controls. N Engl J Med, 1975; 292: 1148-51.

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