FREQUENCY AND PATTERN OF PSYCHIATRIC DISORDERS IN PATIENTS WITH VITILIGO

Authors

  • Ijaz Ahmed
  • Sohail Ahmed
  • Sarwat Nasreen

Abstract

Background: Vitiligo affects one to four percent of the population, regardless of age, race or sex.People with this disorder may experience emotional stress, particularly if vitiligo develops onvisible areas of the body, such as face, hands, arms, feet, or on the genitals. Some feelembarrassed, ashamed, depressed, or worried about how others will react. Severel indices havebeen used from time to time to measure the extent of psychiatric disabilty caused by skindisorders. Regarding vitiligo, not much work has been done in Pakistan. This study was aimed todetermine the frequency and pattern of psychiatric disorders amongst patients with vitiligo.Methods: This cross sectional study was conducted in the Departments of Psychiatry andDermatology, Ziauddin University, KDLB campus, Karachi and Institute of Surgery andMedicine, Karachi from April 2004 to March 2006. Clinically diagnosed cases of vitiligo,belonging to both sexes, aged above 15 years, fulfilling the inclusion criteria were enrolled in thestudy. The study was conducted in 2 stages. In the first stage, psychiatric illness was detected withthe help of GHQ 12 (Urdu version), a validated tool for screening general population. In thesecond stage, “Psychiatric Assessment Schedule”, Urdu version was administrated to every patientwith high scores as per GHQ 12 to differentiate between the most frequent psychiatric disorders.All the findings were recorded, compiled and tabulated. Results: A total of 100 patientscomprising 62 females and 38 males ranging between 15-60 years with a mean age of 24.6 yearscompleted the study. Exposed parts of the body were involved in 64 patients while covered sites in36. Of the patients studied, 54 were married and 46 unmarried. In accordance with the GHQ-12screening, 42 patients were positive for psychiatric caseness comp rising 26 females and 16 males,17 patients being married. Psychiatric caseness featured in patients below 30 years of age(28 patients) and those having exposed parts of the body being involved (27 patients). Onevaluation with Psychiatric Assessment Schedule (PAS), major depressive illness (15), was themost frequent psychiatric illness followed by generalized anxiety (10), mixed anxiety anddepression, social phobia, agarophobia and sexual dysfunction. Conclusion: Psychiatric casenesshas a probable association with vitiligo, the frequency being influenced by variables of disease andlife. Major depression and anxiety remain the most common psychiatric disorders in thesepatients.Keywords: Vitiligo, Psychiatric caseness, depression, Anxiety

References

Hussain A, Khalid M, Shaheen JA, Ahmed I. Prevalence and

pattern of psychiatric disorders among dermatological

patients. J Pak Assoc Dermatol. 2005; 15: 13-17.

Mattoo SK, Handa S, Kaur I, Gupta N, Malhotra R.

Psychiatric morbidity in vitiligo: prevalence and correlates in

India. J Eur Acad Dermatol Venereol. 2002; 16(6):573–8.

Parsad D, Dogra S, Kanwar AJ. Quality of life in patients

with vitiligo. Health Qual Life Outcomes 2003; 1(1): 58.

Hill-Beuf A, Porter JD. Children coping with impaired

appearance. Social and psychological influences. Gen Hosp

Psychiatry. 1984; 6(4):294–301.

Koo JY, Do JH, Lee CS. Psychodermatology. J Am Acad

Dermatol 2000; 43(5Pt 1):848-53.

Rubinow DR, Peck GL, Squillace KM, Gantt GG. Reduced

anxiety and depression in cystic acne patients after successful

treatment with oral isotretinoin. J Am Acad Dermatol 1987;

(1):25-32.

Noor SM, Khurshid K, Mahmmod T, Haroon TS. Quality of

life in vitiligo. J Pak Assoc Dermatol. 2004; 14: 55-8.

Papadopoulos L, Bor R, Legg C, Hawk JL. Impact of life

events on the onset of vitiligo in adults, preliminary evidence

for psychological dimension in aetiololgy. Clin Exp

Dermatol 1998; 23(6): 243-8.

Porter J, Beuf AH, Lerner A, Nordlund J. Response to

cosmetic disfigurement: patients with vitiligo. Cutis. 1987;

(6): 493-4.

Sharma N, Koranne RV, Singh RK. Psychiatric morbidity in

psoriasis and vitiligo: a comparative study. J Dermatol. 2001;

(8): 419-23.

Minhas FA, Iqbal K, Mubashir MH. Validation of self-rating

questionnaire in primary care setting of Pakistan. Pak J Clin

Psychiatry 1995; 5: 60-5.

Porter JR, Beuf AH, Lerner AB, Nordlund JJ. The effect of

vitiligo on sexual relationship. J Am Acad Dermatol. 1990;

(2 Pt 1): 221–222.

Ginsburg IH, Link BG. Feelings of Stigmatization in Patients

with Psoriasis. J Am Acad Dermatol. 1989; 20(1): 53-63.

Zigmond AS, Snaith RP. The hospital anxiety and depression

scale. Acta Psychiatr Scand. 1983; 67(6): 361-370.

Smart L, Wegner DM. Covering up what can't be seen:

concealable stigma and mental control. J Pers Soc Psychol.

;77(3):474-486.