CHANGES IN BLOOD GLUCOSE AND LIPID PROFILE DURING RAMADAN FASTING

Jamil -ur- Rehman, Mohammad Shafiq

Abstract


Background: It is an established fact that fasting influences carbohydrate and lipid metabolism resulting in changes
in blood levels of glucose and lipid profile. This study describes the changes observed in the volunteers who fasted
throughout the month of Ramadan. Methods: After screening. 24 volunteers were included in the study on the basis
of their fasting blood glucose and cholesterol levels and different tests were conducted on serum. Results: Blood
glucose, cholesterol. TAG and LDL-C levels decreased significantly, while HDL-C level rose considerably at the end
of month. But the blood chemistry picture almost returned back to the pre-Ramadan level once fasting was
discontinued for two weeks. Conclusion: It can therefore, be interpreted that the beneficial changes observed during
the month of Ramadan are transient and could only be maintained if the dietary habits of Ramadan are continued
afterwards.

References


El-Hazmi, M.A.F., Al-Faleh, F.Z. and Al-Mofleh, I.A. Effect

of Ramadan fasting on value of haematological and

biochemical parameters. Saudi Med. J., 1987; 8: 171-6.

Bhagavan, N.V. Carbohydrate metabolism I. Glycolysis and

TCA cycle. In; Medical Biochemistry, second edition, Jones

and Bartlett Publishers London. 1992: pp 237-259.

Mayes, P.A. Cholesterol synthesis, transport and excretion, In;

Harper’s biochemistry', 23n edition, Murray, R.K. et al. (eds),

Appleton and Lange, East Norwalk, 1993: pp. 266-78.

Stryer, L. Fatty acid metabolism, In; Biochemistry', second

edition, W.H. Freeman and Company, San Francisco, 1981:

pp. 383-405.

Qureshi, M.H., Naseer, F. and Haq, I. Effect of Fasting

(Islamic) on blood glucose and cholesterol levels. J.M.S.,

;3:24-5.

JAMC, Vol. 12, No. 3, 2000

Aziz, K. Raja, R.J. and Marri. S.M. Variation in lipid profile

during fasting in Ramadan in healthy male adults. J. P.M.A.,

; 42(10): 242-3.

Friedwald, W.T., Levy, R.I. and Fredrickson, D.S.

Estimation of the concentration of LDL-Cholesterol in plasma,

without use of the preparative ultra-centrifuge. Clin. Chem.,

: 18(6): 499-502.

Lehninger, A.L., Nelson, D.L. and Cox, M.M.

Carbohydrate biosynthesis, In; Principles of biochemistry,

second edition. Worth Publishers Inc., U.S.A., 1993; pp.598-

Chill, G.F. Jr. Starvation in man. Clin. Endocrinol.

Metab., 1976; 5: 397-415.

Mayes, P.A. Gluconeogenesis and control of blood glucose,

In; Harper’s biochemistry, 23rd edition, Murray. R.K. et al

(eds), Appleton and Lange, East Norwalk, 1993: pp. 190-200


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