PREVALENCE OF CARDIORENAL SYNDROME IN PATIENTS ADMITTED FOR ACUTE DECOMPENSATED HEART FAILURE AND ITS CORRELATION WITH IN-HOSPITAL OUTCOMES
Keywords:
Prevalence, Cardiorenal syndrome, In-hospital, tertiary careAbstract
Background: Cardiorenal syndrome is the prevalent form of the syndrome in Pakistan. Despite the rising importance of CRS, more information is needed to understand comorbidities and hospital outcomes. This research study explores the prevalence, and In-hospital outcomes of patients admitted for Acute Decompensated Heart Failure at the tertiary care hospital of Islamabad at the age of above 18. Methods: This cohort study was conducted at the tertiary care hospital in Islamabad from January 2024 to June 2024. Data were collected from 200 known ADHF patients who visited the CCU (OPD) and ward through a structured questionnaire. The data were analyzed using SPSS version 25. Result: The majority of the sample was diagnosed with Type 1 Cardiorenal Syndrome, which accounted for 30% of the total. Cardiorenal Syndrome Types 3 and 5 had a prevalence of 20% each among the patients, while Types 2 and 4 had a prevalence of 15% each. This suggests that Type 1 was more prevalent, but the other types were equally distributed. The mortality rate in the Hospital was highest for Type 5 CRS at 15% and Type 3 CRS at 13%. During this period, Type 2 CRS exhibited the lowest mortality rate. Type 3 CRS had the most extended average hospitalization duration. Conclusion: It was concluded in our study that cardiorenal syndrome is the prevalent form among admitted patients with ADHF, and the government needs to increase awareness about health and health-related risk factors related to the communities.
References
1. House AA, Anand I, Bellomo R, Cruz D, Bobek I, Anker SD, Aspromonte N, Bagshaw S, Berl T, Daliento L, Davenport A. Definition and classification of Cardio-Renal Syndromes: workgroup statements from the 7th ADQI Consensus Conference. Nephrology Dialysis Transplantation. 2010 May 1;25(5):1416-20.
2. Bargshaw SM, Cruz DM, Aspromonte N, Acute Dialysis Quality Initiative. Epidemiology of cardio–renal syndromes: workgroup statements from the 7th ADQI Consensus Conference. Nephrol Dial Transplant. 2010;25(5):1406-16.
3. Dar O, Cowie MR. Acute heart failure in the intensive care unit: epidemiology. Critical Care Medicine. 2008 Jan 1;36(1):S3-8.
4. Aronson D. Cardiorenal syndrome in acute decompensated heart failure. Expert review of cardiovascular therapy. 2012 Feb 1;10(2):177-89.
5. Blair JE, Pang PS, Schrier RW, Metra M, Traver B, Cook T, Campia U, Ambrosy A, Burnett Jr JC, Grinfeld L, Maggioni AP. Changes in renal function during hospitalization and soon after discharge in patients admitted for worsening heart failure in the placebo group of the EVEREST trial. European heart journal. 2011 Oct 1;32(20):2563-72.
6. Zahoor S, Arshad MS, Riaz A, Farhan M. Precipitants of acute decompensated heart failure and their correlation with the severity of decompensation in a resource poor country. Journal of Islamabad Medical & Dental College. 2017;6(4):219-23.
7. DeFrances CJ, Lucas CA, Buie VC, Golosinskiy A. 2006 national hospital discharge survey. Natl Health Stat Report. 2008 Jul 30;5(July):1-20.
8. Zaidi M, Rehman AJ, Haque A, Akhtar S, Maheshwar PK. Frequency of cardiorenal syndrome type-I in hospitalized children with acute heart failure in a tertiary-care hospital. JCPSP: Journal of the College of Physicians and Surgeons Pakistan. 2014;24(8):577.
9. Naqvi R. Thrombotic Microangiopathy and acute kidney injury with malaria: One-year experience at SIUT. Pakistan Journal of Kidney Diseases. 2024 Jun 30;8(2):23-6.
10. Usman MS, Khan MS, Butler J. The interplay between diabetes, cardiovascular disease, and kidney disease.
11. Ronco C, McCullough P, Anker SD, Anand I, Aspromonte N, Bagshaw SM, Bellomo R, Berl T, Bobek I, Cruz DN, Daliento L. Cardio-renal syndromes: report from the consensus conference of the acute dialysis quality initiative. European heart journal. 2010 Mar 1;31(6):703-11.
12. Ronco C, Di Lullo L. Cardiorenal syndrome in western countries: epidemiology, diagnosis and management approaches. Kidney diseases. 2017 Sep 10;2(4):151-63.
13. Zarbock A, Küllmar M, Ostermann M, Lucchese G, Baig K, Cennamo A, Rajani R, McCorkell S, Arndt C, Wulf H, Irqsusi M. Prevention of cardiac surgery–associated acute kidney injury by implementing the KDIGO guidelines in high-risk patients identified by biomarkers: The PrevAKI-multicenter randomized controlled trial. Anesthesia & Analgesia. 2021 Aug 1;133(2):292-302.
14. Syed M. Hyponatremia in acute decompensated heart failure as a predictor of acute cardiorenal syndrome Type-1. Indian Journal of Cardiovascular Disease in Women. 2023 Apr 11;8(2):121-5.
15. Maisons V, Halimi JM, Fauchier G, de Fréminville JB, Goin N, Gueguen J, Gatault P, Sautenet B, Angoulvant D, Herbert J, Bisson A. Type 2 diabetes and cardiorenal syndromes. A nationwide French hospital cohort study. Diabetes & Metabolism. 2023 May 1;49(3):101441.
16. Prothasis, M., Varma, A., Gaidhane, S., Kumar, S., Khatib, N., Zahiruddin, Q. S., & Gaidhane, A. (2020). Prevalence, types, risk factors, and outcomes of cardiorenal syndrome in a rural population of central India: A cross-sectional study. Journal of Family Medicine and Primary Care, 9(8), 4127-4133.
17. Liu M, Li XC, Lu L, Cao Y, Sun RR, Chen S, Zhang PY. Cardiovascular disease and its relationship with chronic kidney disease. European Review for Medical & Pharmacological Sciences. 2014 Oct 1;18(19).
18. Kumar A, Shandil R, Gupta D, Ganju N, Shandil A, Shandil A. Clinical profile and outcome of patients with cardiorenal syndrome type 1: a cross sectional observational study. Eur J Cardiovasc Med. 2023;13(4).
19. Nakayama M. Nonuremic indication for peritoneal dialysis for refractory heart failure in cardiorenal syndrome type II: review and perspective. Perit Dial Int. 2013;33(1):8-14.
20. Gigante A, Liberatori M, Gasperini ML, Sardo L, Di Mario F, Dorelli B, Barbano B, Rosato E, Rossi Fanelli F, Amoroso A. Prevalence and clinical features of patients with the cardiorenal syndrome admitted to an internal medicine ward. Cardiorenal Medicine. 2014 May 6;4(2):88-94.
21. Pimienta González R, Couto Comba P, Rodríguez Esteban M, Alemán Sánchez JJ, Hernández Afonso J, Rodríguez Pérez MD, Marcelino Rodríguez I, Brito Díaz B, Elosua R, Cabrera de León A. Incidence, mortality and positive predictive value of type 1 cardiorenal syndrome in acute coronary syndrome. PLoS One. 2016 Dec 1;11(12):e0167166.
22. Dreznik Y, Hoffman A, Hamburger T, Ben-Yaacov A, Dux Y, Jacoby H, Berger Y, Nissan A, Gutman M. Hospital readmission rates and risk factors for readmission following cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal surface malignancies. the surgeon. 2018 Oct 1;16(5):278-82.
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