TAKAYASU ARTERITIS IN A YOUNG FEMALE PRESENTING WITH PYREXIA OF UNKNOWN ORIGIN IN THE PRE-PULSELESS PHASE

Authors

  • Abeera Farooq Ayub Medical College
  • Fatima Sheraz
  • Tehzeeb Zehra Shifa college of medicine
  • Hayida Ali shifa college of medicine
  • Muhammad Jahangir adil shifa college of dentistry
  • Sheema Farid
  • Romana Irshad Ayub Medical College

DOI:

https://doi.org/10.55519/JAMC-02-14695

Abstract

Takayasu arteritis is a rare chronic large vessel vasculitis that mainly occurs in young females with a higher prevalence in Asian population. This disease, in its early stages, often goes undiagnosed because of its non-specific and vague symptoms. This poses great difficulty for doctors to accurately make the diagnosis. One of its initial presentations is 'pyrexia of unknown origin (PUO). PUO precedes the pulseless stage of Takayasu arteritis. Here we're going to do a case report on a 26-year-old female patient presenting with PUO as the pre-pulseless stage of Takayasu arteritis. The presentation as PUO in the absence of pulse deficits is very uncommon and has been very underwhelmingly reported.

Author Biography

Romana Irshad, Ayub Medical College

Assistant Professor,Pathology department ,Ayub Medical  college, Abbottabad

References

1. David A, Quinlan JD. Fever of Unknown Origin in Adults. Am Fam Physician. 2022 Feb 1;105(2):137-143. PMID: 35166499.

2. Fernandez C, Beeching NJ. Pyrexia of unknown origin. Clin Med (Lond). 2018 Mar;18(2):170-174. doi: 10.7861/clinmedicine.18-2-170. PMID: 29626024; PMCID: PMC6303444.

3. Onen F, Akkoc N. Epidemiology of Takayasu arteritis. Presse Med. 2017 Jul-Aug;46(7-8 Pt 2):e197-e203. doi: 10.1016/j.lpm.2017.05.034. Epub 2017 Jul 26. PMID: 28756072.

4. Unnikrishnan S, Ingle V, Singhai A, Pandita K, Atlani M. Takayasu Arteritis in the Pre-Pulseless Phase Presenting as Pyrexia of Unknown Origin. Cureus. 2023 Sep 24;15(9):e45855. doi: 10.7759/cureus.45855. PMID: 37881385; PMCID: PMC10597183

5. Unnikrishnan S, Ingle V, Singhai A, Pandita K, Atlani M. Takayasu Arteritis in the Pre-Pulseless Phase Presenting as Pyrexia of Unknown Origin. Cureus. 2023 Sep 24;15(9):e45855. doi: 10.7759/cureus.45855. PMID: 37881385; PMCID: PMC10597183.

6. Achari V, Prakash S. Takayasu's disease presenting with pain chest, prolonged pyrexia and pleural effusion. J Assoc Physicians India.2005 Aug;53:722-4. PMID: 16398084

7. Chung SA, Langford CA, Maz M, Abril A, Gorelik M, Guyatt G, et al. 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol. 2021 Aug;73(8):1366-1383. doi: 10.1002/art.41773. Epub 2021 Jul 8. PMID: 34235894.

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Published

2025-06-15

How to Cite

1.
Farooq A, Sheraz F, Zehra T, Ali H, Jahangir adil M, Farid S, et al. TAKAYASU ARTERITIS IN A YOUNG FEMALE PRESENTING WITH PYREXIA OF UNKNOWN ORIGIN IN THE PRE-PULSELESS PHASE. J Ayub Med Coll Abbottabad [Internet]. 2025 Jun. 15 [cited 2025 Nov. 22];37(2):250-2. Available from: https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/14695