COMPARATIVE ANALYSIS OF TYPE OF MYOCARDIAL INFARCTION IN PATIENTS WITH SUCCESSFUL OR UNSUCCESSFUL STREPTOKINASE THROMBOLYSIS FOLLOWING ST ELEVATION MYOCARDIAL INFARCTION
Abstract
Objective: To study the effect of thrombolytic therapy in term of success and failure on the type of STelevation MI, using streptokinase. Material and Methods: This was a comparative study, conducted at
Department of Cardiology, Lady Reading Hospital, Peshawar, from October 2006 to October 2007.
Patients with first acute myocardial infarction were divided into group A (successful thrombolysis) and
group B (unsuccessful thrombolysis) using ECG criteria. Results: Total number of patients were 200.
Group A included 136 (68%) patients and group B included 64 (32%) patients. There were total 88
(44%) patients of anterior MI with 47 patients in group A and 41 patients in group B (34.6% vs 64.0%,
p<0.001). There were total 110 (55.0%) patients of inferior MI with 88 patients in group A and 22
patients in group B (64.7% vs 34.4%, p<0.001). Lateral myocardial infarction was diagnosed in 2 (1%)
patients with 1 patient each in group A and group B (0.7% vs 1.6%, p=0.583). Conclusion: Anterior
MI was associated with a higher rate of thromblysis failure while inferior MI and lateral wall MI was
associated with a higher rate of successful thrombolysis.
Keywords: Myocardial infarction; thrombolysis; type of myocardial infarction
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