PERCEPTION OF ACADEMIC EXAMINATION STRESS: EFFECTS ON SERUM LEPTIN, CORTISOL, APPETITE AND PERFORMANCE
Abstract
Background: Examination stress is a psychological stress that activate hypothalamic-pituitaryadrenocortical (HPA) axis to increase circulating levels of glucocorticoids. The fat derived
hormone leptin is also released in response to stress-inducing condition. To workout the role of
leptin and cortisol in response to perceived levels of examination stress and their effects on
academic performance. The present study was designed to monitor the relationship of self reported
perceived levels of examination stress on serum levels of cortisol and leptin in female students
going to appear in university examination. Methods: Fifty-six female undergraduate students
participated in the study. Examination stress, appetite levels were assessed by a questionnaire and
blood samples were collected one hour before appearing in the examination. Performance was
evaluated from the marks obtained in that particular examination. Results: Serum cortisol levels
increased with an increase in the intensity of perceived examination stress. Serum leptin levels
increased only in the group under moderate stress while increases in mild and severe stress group
were not significant. Mild to moderate stress enhanced performance but severe stress decreased it.
Conclusions: The present study shows an inverted U-shaped relationship between self reported
different levels of perceived examination stress and academic performance.
Keywords: Academic Stress, Cortisol, Leptin, Appetite, Performance
References
Knapman A, Heinzmann JM, Hellweg R, Holsboer F, Landgraf R,
Touma C. Increased stress reactivity is associated with cognitive
deficits and decreased hippocampal brain-derived neurotrophic
factor in a mouse model of affective disorders. J Psychiatr Res
;44:566-75.
Raison CL, Miller AH. When not enough is too much: the role of
insufficient glucocorticoid signaling in the pathophysiology of
stress-related disorders. Am J Psychiatry 2003;160:1554-65.
Tsigos C, Chrousos GP. Hypothalamic-pituitary-adrenal axis,
neuroendocrine factors and stress. J Psychosom Res 2002;53:865-71.
Dagogo-Jack S, Umamaheswaran I, Askari H, Tykodi G. Leptin
response to glucocorticoid occurs at physiological doses and is
abolished by fasting. Obes Res 2003;11:232-7.
Askari H, Liu J, Dagogo-Jack S. Hormonal regulation of human
leptin in vivo: effects of hydrocortisone and insulin. Int J Obes
Relat Metab Disord 2000;24:1254-9.
Otsuka R, Yatsuya H, Tamakoshi K, Matsushita K, Wada K,
Toyoshima H. Perceived psychological stress and serum leptin
concentrations in Japanese men. Obesity (Silver Spring)
;14:1832-8.
Liao SC, Lee MB, Lee YJ, Huang TS. Hyperleptinemia in
subjects with persistent partial posttraumatic stress disorder after a
major earthquake. Psychosom Med 2004;66:23-8.
Lu XY, Kim CS, Frazer A, Zhang W. Leptin: a potential novel
antidepressant. Proc Natl Acad Sci U S A 2006;103:1593-8.
Cohen S, Kamarck T and Mermelstein R. A global measure
perceived stress. J. Health. Soc. Behav 1983;24:385-96.
Kyrou I, Tsigos C. Stress hormones: physiological stress and
regulation metabolism. Curr Opin Pharmacol 2009;9:787-93.
Pervanidou P, Chrousos GP. Neuroendocrinology of posttraumatic stress disorder. Prog Brain Res 2010;182:149-60.
Kawada T, Miyamoto T, Miyoshi Y, Yamaguchi S, Tanabe Y,
Kamiya A, et al. Sympathetic neural regulation of heart rate is
robust against high plasma catecholamines. J Physiol Sci
;56:235-45.
Al-Ayadhi LY. Neurohormonal changes in medical students
during academic stress. Ann Saudi Med 2005;25:36-40.
Lo Sauro C, Ravaldi C, Cabras PL, Faravelli C, Ricca V. Stress,
hypothalamic-pituitary-adrenal axis and eating disorders.
Neuropsychobiology 2008;57:95-115.
Grossniklaus DA, Dunbar SB, Tohill BC, Gary R, Higgins MK,
Frediani J. Psychological factors are important correlates of dietary
pattern in overweight adults. J Cardiovasc Nurs 2010;25:450-60.
Woldt L, Schneider N, Pfeiffer E, Lehmkuhl U, Salbach-Andrae
H. Psychiatric disorders among parents of patients with anorexia
nervosa and bulimia nervosa. [Article in German]. Prax
Kinderpsychol Kinderpsychiatr 2010;59:302-13.
Salehi B, Cordero MI, Sandi C. Learning under stress: the
inverted-U-shape function revisited. Learn Mem 2010;17:522-30.
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