GYNAECOMASTIA: MANAGEMENT IN A DEVELOPING COUNTRY
Abstract
Background: Gynaecomastia is a benign enlargement of male breast. It is common in the generalpopulation, resulting from various pathophysiological mechanisms. The aim of this study was to
describe the presentation and outcome of treatment for gynaecomastia at a University Hospital in
Pakistan. Methods: A three year retrospective study was carried out of one hundred men with
gynaecomastia. Patients were evaluated in detail clinically and by appropriate investigations. They were
counselled and kept on hormonal therapy for three months. Surgery was considered for patients with
long standing gynaecomastia, failed medical therapy and for cosmetic reasons. Post operative
complications and patient's satisfaction was assessed. Results: Most (90%) cases were idiopathic.
Other causes were liver cirrhosis in 4 cases, testicular tumour in two, thyrotoxicosis in one and drug
induced (use of cimetidine and Kushta) in two. Carcinoma of the breast was diagnosed in one patient.
Most of the patients had bilateral, non tender lump in the breast. Three cases of idiopathic
gynaecomastia resolved on danazol. Eighty-eight cases underwent surgical treatment. The mean age of
patients who underwent surgery (n=88) was 30.5±9.59 years. Most of the patients belonged to 21-30
years age group. Major indications for surgery were failure of medical treatment (45.5%) and cosmetic
reasons (34.0%). Mean operating time for subcutaneous mastectomy was 42.2±3.70 (36-48) minutes.
Mean hospital stay after subcutaneous mastectomy was 5.2±2.44 (2-10) days. The only postoperative
complication noted was wound infection (24%). Seventy-two (81.8%) were satisfied with the results of
their surgical treatment. Conclusion: Gynaecomastia is the common condition affecting male breasts
and most common cause of gynaecomastia is idiopathic. Secondary gynaecomastia may regress in size
by treating the primary cause. Idiopathic gynaecomastia do not respond to danazol so they needed
surgical treatment. Subcutaneous mastectomy through a periareolar skin incision is a valid procedure
for treatment for gynaecomastia and provides satisfactory cosmetic results.
Keywords: Gynaecomastia, Male breast, Management, Subcutaneous mastectomy
References
Braunstein GD. Gynecomastia. N Engl J Med 1993;328:490-5.
Matarasso SL. Liposuction of the chest and back. Dermatol Clin
;17:799-804.
Celebioglu S, Ertas NM, Ozdil K, Oktem F. Gynecomastia
treatment with subareolar glandular pedicle. Aesth Plast Surg
;28:281-6.
McGrath MH, Mukerji S. Plastic surgery and the teenage patient.
J Pediatr Adolesc Gynecol 2000;13:105-18.
Gasperoni C, Salgarello M, Gasperoni P. Technical refinements
in the surgical treatment of Gynaeco-mastia. Ann Plast Surg
;44:455-8.
Wallace AM: Gynecomastia In: Evans GRD (ed) Operative
plastic surgery. New York: McGraw-Hill; 2000.p. 686-97.
Mathur R, Braunstein GD. Gynecomastia: pathomechanisms and
treatment strategies. Horm Res 1997;48:95-102.
Volpe CM, Raffetto JD, Collure DW, Hoover EL, Doerr RJ.
Unilateral male breast masses: Cancer risk, and their evaluation
and management. Am Surg 1999;65(3):250-3.
Giordano SH, Buzdar AU, Hortobagyi GN. Breast cancer in men.
Ann Intern Med 2002;137:678-87.
Colonna MR, Baruffaldi Preis FW, Ponzielli G, Cavallini
M, Giovannini UM, Di Leo A. Gynecomastia: diagnostic and
surgical approach in the treatment of 61 patients. Ann Ital Chir
;70(5):699-703.
Nydick M, Bustos J, Dale JH, Rawson RW. Gynecomastia in
adolescent boys. JAMA 1961;178:109-14.
Hands LJ, Greenall MJ. Gynaecomastia. Br J Surg 1991;78:907-11.
Nuttal FQ. Gynaecomastia as a physical finding in normal men. J
Endocrinol 1979;48:338-40.
Biro FM, Lucky AW, Huster GA, Morrison JA. Hormonal
studies and physical maturation in adolescent gynaecomastia. J.
Pediatr 1990;116:450-5.
Einav-Bachar R, Phillip M, Aurbach-Klipper Y, Lazar L.
Prepubertal gynaecomastia: aetiology, course and outcome. Clin
Endocrinol (Oxf) 2004;61(1):55-60.
August GP, Chandra R, Hung W. Prepubertal male
gynecomastia. J Pediatr 1972;80(2):259-63.
Bembo SA, Carlson HE. Gynaecomastia: its features, and when
and how to treat it. Cleve Clin J Med 2004;71:511-7.
Wiesman IM, Lehman JA, Parker MG, Tantri MD, Wagner
DS, Pedersen JC. Gynecomastia-an outcome analysis. Ann Plast
Surg 2004; 53: 97-101.
Colombo-Benkmann M, Buse B, Stern J, Herfarth C. Indications
for and results of surgical therapy for male gynecomastia. Am J
Surg 1999;178:60-3.
Chantra PK, So GJ, Wollman JS, Bassett LW. Mammography of
the male breast. Am J Roent 1995;165:853-8.
Jackson VP. Gilmor RL. Male breast carcinoma and
gynecomastia: comparison of mammography with sonography.
Radiology 1983;149:533-6.
Cole-Beuglet C, Schwartz GF, Kurtz AB, Patchefsky AS,
Goldberg BB. Ultrasound mammography for male breast
enlargement. J Ultrasound Med 1982;1:301-5.
Daniels IR, Layer GT. Gynaecomastia. Eur J Surg 2001;167:885-
Gupta RK, Naran S, Dowle CS, Simpson JS. The diagnostic
impact of needle aspiration cytology of the breast on clinical
decision making with an emphasis on the aspiration cytodiagnosis
of the male breast. Diagn Cytopathol 1991;7:637-9.
Joshi A, Kapila K, Verma K. Fine needle aspiration cytology in
the management of male breast masses. Nineteen years of
experience. Acta Cytol 1999;43:334-8.
Webster JP. Mastectomy for gynaecomastia through a
semicircular intra-areolar incision. Ann Surg 1946;124:557-75.
Simon BE, Hoffman S, Kahn S. Classification and surgical
correction of gynaecomastia. Plast. Reconstr. Surg 1973;51:48-52.
Persichetti P, Berloco M, Casadei RM, Marangi GF, DiLella F,
Nobili AN. Gynaecomastia and the complete circumareolar
approach in the surgical management of skin redundency. Plast
Reconstr Surg 2001;107:948-53.
Steele SR, Martin MJ, Place RJ. Gynecomastia: complications of
the subcutaneous mastectomy. Am Surg 2002;68:210-3.
Tashkandi M, Al-Qattan MM, Hassanain JM, Hawary MB,
Sultan M. The surgical management of high-grade gynecomastia.
Ann Plast Surg 2004;53:17-20.
Fruhstorfer BH, Malata CM. A systemic approach to the surgical
treatment of gynaecomastia. Br J Plast Surg 2003;56:237-46.
Aslan G, Tuncali D, Terzioglu A, Bingul F. Periareolartransareolar-perithelial incision for the surgical treatment of
gynecomastia. Ann Plast Surg 2005;54:130-4.
Samdal F, Kleppe C, Amland PF, Abyholm F. Surgical treatment
of Gynaecomastia: Five years' experience with liposuction. Scand
J Plast Reconstr & Hand Surg 1994;28:123-30.
Hodgson ELB, Fruhstorfer BH. and Malata CM. Ultrasonic
Liposuction in the treatment of gynaecomastia. Plast Reconstr
Surg 2005;116:646-53.
Pitanguy I. Transareolar incision for gynaecomastia. Plast
Reconstr Surg 1966;38:414-9.
Gabra HO, Morabito A, Bianchi A, Bowen J. Gynaecomastia in
the Adolescent: A Surgically Relevant Condition. Eur J Pediatr
;14:3-6.
Downloads
Published
How to Cite
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.