MATERNAL SERUM LEVELS OF ADIPONECTIN IN PREECLAMPSIA
Abstract
Background: The results of the serum levels of adiponectin in preeclamptic patients areconflicting. Objective: The aim of the present study was to assess serum levels of adiponectin in
women with preeclampsia compared with healthy pregnant women. Methods: A cross-sectional
study was designed. The case group consisted of women with preeclampsia (n=30). The control
group consisted of 30 matched normal pregnant women. Serum levels of adiponectin were
assessed using enzyme-linked immunosorbent assay method. Results: Serum levels of adiponectin
were significantly higher in the preeclamptic group than those in the normal control group. In the
preeclamptic patients serum levels of adiponectin showed a significant negative correlation with
body mass index while no correlation was found in the normal pregnant women. In women with
preeclampsia, levels of adiponectin were decreased significantly in the overweight women
compared with normal weight women, while in the control group no significant difference was
observed. Conclusion: In conclusion, elevation of adiponectin levels might be a physiological
feedback response to minimize endothelial dysfunction in preeclamptic patients.
Keywords: Serum, Adiponectin, Preeclampsia, Pregnancy, BMI, ELISA.
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