CLINICAL SPECTRUM AND MANAGEMENT OF OVARIAN TUMOURS IN YOUNG GIRLS UPTO 20 YEARS OF AGE
Abstract
Background: Ovarian tumours are one of the common malignancies all over the world affecting allage groups. This study analyses different clinical presentation and management of ovarian tumours
in young girls up to 20 years. Methods: Patients up to 20 years of age admitted with the diagnosis of
ovarian tumour were included. Data collected on a proforma. Variables studied included age,
presenting symptoms, investigations, surgical findings, type of surgery, histopathology reports and
follow-up. The patients with malignant ovarian tumour were followed by oncologist as well as
gynaecologist. Data analysis was done on SPSS. Results: The mean age was 17.27±2.46 SD years.
The common symptoms included abdominal mass, abdominal pain, urinary problems, menstrual
irregularities and generalized malaise. All patients were operated after preliminary investigations.
Patients were advised to have follow-up post-operatively after 1 month. The follow up was done by
oncologist and gynaecologist. Six patients (12.5%) died and 22 (45.83%) were lost to follow up.
Conclusion: Ovarian tumours are quite common in young girls. Majority of patients seek medical
advice once the disease becomes symptomatic, complicated or advanced disease in the case of
malignancy. Histopathology of the tumours revealed that epithelial cell tumour is the commonest
tumour in contrast to germ cell tumour as reported by world literature.
Keywords: Ovarian tumours, Young age, Conservative surgery, Teratoma, Neoplasm
References
Hassan E, Creatsas G, Michalas S. Genital tumours during
childhood and adolescence: a clinical and pathological study
of 71 cases. Clin Exp Obstet Gynecol 1999;26:20-1.
Iffat N, Saima M, Malik SS. Review of ovarian tumours. Ann
King Edward Med Coll 2001;7:180-2.
Ahmed Z, Kayani N, Hasan S, Muzaffr S, Gill M.
Histological pattern of ovarian neoplasms. J Pak Med Assoc
;50:416-9.
Mariam M, Farooq A. Malignant ovarian tumours: a study of
patients. Pak J Obstet Gynaecol 1999;12:83-6.
Shahin R, Ghulam S, Abid A. A clinico-pathological study of
ovarian cancer. Mother & Child 1998;36:117-25.
Rieber A, Nussle K. Preoperative diagnosis of ovarian
tumours with MR imaging, comparison with transvaginal
sonography, positron emission tomography and histological
findings. AJR Am J Roentgenol 2001;177:123-9.
Horejsi J, Rob L. Malignant tumours of the female genitalia
in childhood-yesterday, today and tomorrow. Cas lek Cesk.
;142:84-7.
Sheikh MA, Akhtar J, Batool T, Naqvi R, Taqvi R, Jalil S, et
al. A study of ovarian lesions in Pre menarche Girls J Coll
Physicians Surg Pak 2007;17:162-5.
Warner MA, Fliescher AC, Edell SL, Theieme GA, Bundy
AL, Kurtz AB. Uterine adnexal torsion: Sonographic findings
radiology 1985;154:773-5.
Sultana A, Hassan S, Siddiqui QA. Ovarian tumours: A five
years retrospective study at Abbasi Shaheed Hospital,
Karachi. Pak J Surg 2005;21:37-40.
Gonzalo, Alonso E, Merino Marcos I, Ferandez-Teijeiro
Alvarez A, Astigarraga Aguirre I, Navajas Gutierrez A.
Ovarian tumours in childhood: apropos of a review of cases.
An Esp. Pediatr 1998;49:491-4.
DePriest PD, Varner E, Powell J, Fried A, Puls L, Higgins R.
The efficacy of a sonographic morphology index in
identifying ovarian cancer: a multi institutional investigation.
Gynecol Oncol 1994;55:174-8.
Rufford BD, Jacobs IJ. Ovarian Cysts in postmenopausal
women. Royal College of obstetricians and gynaecologists
Guideline No. 34, 2003; p 321-8.
Jacobs I, Oram D, Fair banks J, Turner J, Frost C, Grud
Zinskas JG. A risk of malignancy index incorporating
CA125, ultrasound and menopausal status for the accurate
pre-operative diagnosis of ovarian cancer. Br J Obstet
Gynecol 1990;97:922-9.
Tuncer ZS, Gunalp S, Aksu T Ayhan A. Benign epithelial
ovarian tumours. Eur J Gynaecol Oncol. 1998;19:391-3.
Edmond DK editors Epithelial ovarian cancer Dewhursts
Text Book of Gynae and Obst 7th Ed. London: Black well
(publisher) Ltd, 2006; p. 625-35.
Deligcoroglou E, Eleftheriades M, Shiadoes V, Botsis D,
Hasiakos D, Kontoravdis A. Ovarian masses during
adolescence: clinical, ultrasonographic and Pathologic
findings, serum tumour markers and endocrinological profile.
Gynecol Endo Crinol 2004;19:1-8.
Rzepka-Górska I, Błogowska A, Zajaczek S, Zielińska D.
Germinal Cell tumours in young and adolescent girls Ginekol
Pol 2003:74:840-6. (Polish Article).
Breen J, Maxon WS. Ovarian tumours in childhood and
adolescence. Clin Obstet Gynecol 1977;20:607-23.
Lu KH, Ger Shenson DM update on the manegment of
ovarian germ cell tumours. J Repord Med. 2005;50:417-25.
Morowitz M, Huff D, Von Allmen D. Epithelial ovarian
tumours in children: a retrospective analysis. J Pediatr Surg.
;38:331-5.
Quint EH, Smith YR. Ovarian surgery in pre menarchal girls.
J Pediatr Adolese Gynecol 1999;12:27-30.
Haefner HK, Roberts JA, Schmidt RW. The university
experience of clinical and pathological findings of ovarian
neplasms in children and adolescents. J Padiatr Adolese
Gynecol 1992;5:182-6.
Rosen DM, Lam AM, Carlton MA, Cario GM. The safety of
laparoscopic treatment for ovarian dermoid tumours. Aust
NZ J Obstet Gynaecol 1998;38:77-9.
Luxman D, Cohen JR, David MP. Laparoscopic conservative
removal of ovarian dermoid cysts. J Am Assoc Gynecol
Laparosc 1996:3:409-11.
Lin P, Falcone T, Tulandi T. Excision of ovarian dermoid
cysts by laparoscopy and by laparotomy. IS J Obstet Gynecol
; 173:769-71.
Kozlowski KJ. Ovarian masses. Adolesc Med 1999;10:337-
, vii.
Lu Kh, Gershenson DM. Update on the management of
ovarian germ cell tumour J Repord Med. 2005;50:417-25.
Kutusheva GF. Neoplasms of the genitalia in young girls.
Vestn Khir Im I I Grek. 2000;159:41-5. (Article Russian).
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