PERCUTANEOUS NEEDLE PERITONEAL BIOPSY IN THE DIAGNOSIS OF EXUDATIVE ASCITES

Authors

  • Khalid Mahmood
  • Mohammad Ilyas Saeedi
  • Riaz Mohammad
  • Zia uddin
  • Mustafa Kamal

Abstract

Background: Percutaneous needle peritoneal biopsy in diagnosis of exudative ascites has gained wide
acceptance and many workers have utilized it with a high diagnostic yield and no significant
complications. Present study has been carried out to determine the efficacy of percutaneous needle
peritoneal biopsy in the diagnosis of exudative ascites of unknown aetiology. Methods: It is a descriptive
case study conducted in Medical '˜C' Unit, Lady Reading Hospital, Postgraduate Medical Institute, Khyber
Medical University Peshawar over a period of 2 years, i.e., from Nov, 2003 to December 2005. A total of
45 patients having unexplained exudative ascites underwent blind needle peritoneal biopsy. The biopsy
specimen was subjected to histopathology. Ascitic fluid was also obtained for analysis. Post biopsy
patients were observed for 24 hours for any untoward complications. Results: A total of 45 patients (17
male and 28 female) with age range from 20 to 65 years and having exudative ascites were studied. The
commonest presentation of our patients was abdominal distension (93.3%), pain abdomen (46.67%), fever
(44.4%) and weight loss (33.3%). Histopathology of the peritoneal biopsies was reported as follows.
Eighteen cases (40%) showed non specific chronic inflammation, 10 (22.2%) cases showed caseating
granulomatous inflammation suggestive of tuberculosis and 6 (13.3%) cases showed metastatic
adenocarcinoma. In one patient peritoneal mesothelioma was reported. In the remaining10 patients
(22.2%) biopsies were either non representative or inconclusive. The ascitic fluid showed predominantly
lymphocytes in 86.6% of cases. Only three patients were reported to be having atypical cells on fluid
cytology. The procedure was found safe. No patient was lost due to complications related to the
procedure. Only one patient had evidence of intra peritoneal bleed. The commonest problem post biopsy
was pain (91.1%) and mild swelling (53.3%) at biopsy site. Conclusion: Peritoneal biopsy is fairly safe
and inexpensive procedure with good diagnostic efficacy in patients with undiagnosed exudative ascites.
Keywords: Peritoneal biopsy, Diagnosis, Exudative ascites

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Published

2008-12-01

How to Cite

Mahmood, K., Saeedi, M. I., Mohammad, R., uddin, Z., & Kamal, M. (2008). PERCUTANEOUS NEEDLE PERITONEAL BIOPSY IN THE DIAGNOSIS OF EXUDATIVE ASCITES. Journal of Ayub Medical College Abbottabad, 20(4), 94–96. Retrieved from https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/3855

Issue

Vol. 20 No. 4 (2008): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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