SECRETION OF CALCIUM IN THE SALIVA OF LONG-TERM TOBACCO USERS

Authors

  • Ghulam Jillani Khan
  • Rashid Mehmood
  • Salah -ud- Din
  • Fida Muhammad Marwat
  • Ihtesham -ul- Haq
  • Jamil-ur- Rehman

Abstract

Background: Secretion of calcium in saliva depends upon salivary flow rates in non-tobacco
users and greater is the rate, lower is the concentration and vice versa. In long-term tobacco users
the taste receptors, a primary site for salivary secretion, are constantly exposed to tobacco for long
time thus presumably affecting the salivary reflex. Therefore the main purpose of the study was to
study the secretion of calcium in the saliva of theses individuals. Methods: Subjects of the study
were divided into smokers, pan, (tobacco-betel-lime "quid") chewers, niswar (moist oral snuff)
dippers and non-tobacco users as controls. Each group was comprised of 20 healthy male adults.
The saliva of each subject was collected under resting condition and following application of
crude nicotine and citric acid solutions to the tip of his tongue. Results: All groups of long-term
tobacco users exhibited significantly higher concentrations of calcium before and after stimulation
when compared with controls .However significant drop was observed in calcium levels of all
groups including controls after stimulation but this drop was more pronounced after stimulation
with citric acid than after stimulation with nicotine. Conclusion: We conclude that higher levels
of calcium are present in the saliva of long-term tobacco users than non users which decreases as
the flow of saliva increases.
Key Words: Saliva, calcium, tobacco users.

References

Tordoff MG. Calcium: Taste, Intake, and Appetite. Physiol

Rev 2001;81:1567-97

Larson PS, Haag HB, Silvette H. Tobacco, Experimental

and Clinical Studies. Baltimore, The Williams and Wilkins

Company,1961.

J Ayub Med Col Abbottabad 2005;17(4)

Reddy MS, Naik SR, Bagga OP, Chuttani, HK. Effect of

chronic tobacco-betel-lime quid chewing on human

salivary secretions. Am J Clin Nutr 1980;33:77-80.

Khan GJ, Mehmood R, Salah-ud-Din, Ihtesham-ul-Haq.

Effects of long-term use of tobacco on taste receptors and

salivary secretion. J Ayub Med Coll 2003;15(1):37-9.

Heintz U. Secretion rate, buffer effect and number of

lactobacilli and streptococcus mutans of whole saliva of

cigarette smokers and non-smokers. Scand J Dent Res

;1:294-301.

Parvinen T. Stimulated Salivary flow rate, pH and

lactobacillus and yeast concentrations in non-smokers and

smokers. Scand J Dent Res 1984;92:315-8.

Pavia DL, Lampman GM, Kriz Jr GS. Introduction to

Organic Laboratory Techniques. A Contemporary

Approach. W B Saunders Company. Philadelphia. 1976:46-

Burgen ASV. The secretion of potassium in saliva. J

Physiol 1956;132:20-39.

Jonhansson I, Ericson T, Steen L. Studies of the effect of

diet on saliva secretion and development and the effect of

fasting on the saliva composition of female subject. J Nutr

;114:2010-20.

Guyton AC, Hall JE. In:Textbook of Medical Physiology.

Harcourt A Health Sciences Company. Philadelphia. WB

Saunders and company. 2000: 738-53.

Ganong WF. Review of Medical Physiology. Appleton and

Lange. Medical Publishing Division. California. 1987:406-

Sewon L, Laine M, Karjalainen S, Doroguinskaia A,

Lehtonen-Veromaa M. Salivary calcium reflects skeletal

bone density of heavy smokers. Arch Oral Biol

;49(5):355-8

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How to Cite

Khan, G. J., Mehmood, R., Din, S. .- ud-., Marwat, F. M., Haq, I. .- ul-., & Rehman, J.- ur-. (2005). SECRETION OF CALCIUM IN THE SALIVA OF LONG-TERM TOBACCO USERS. Journal of Ayub Medical College Abbottabad, 17(4). Retrieved from https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/4199

Issue

Vol. 17 No. 4 (2005): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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