GRANULOMATOUS MASTITIS: A REVIEW OF 14 CASES
Abstract
Background: Tuberculosis of breast is a rare entity and may be confused with carcinoma of thebreast. We present a case series of 14 patients with granulomatous mastitis, seen over a seven-year
period from a cancer centre in Lahore, Pakistan. Methods: The cases were retrieved using
electronically coded records and clinical, radiological and pathological data reviewed. Cases with
a histologic diagnosis of granulomatous mastitis were included. Results: Granulomatous mastitis
was seen at a frequency of 0.37% of the 3768 patients seen with breast diseases (3722 women; 46
men) during this time period. The average age at presentation was 40.7 years [range 14- 65 years].
The most common presentation was a lump in the upper outer quadrant of the breast.
Mammography showed a range of appearances. Diagnosis was obtained via fine needle aspiration
(10 cases), core biopsy (2 cases) and excision (2 cases). Acid-fast bacilli were seen in five out of
the 14 patients. Ten out of 14 patients completed treatment at our centre with satisfactory
response. Conclusions: Granulomatous mastits is an uncommon disease and typically presents
with a lump in the breast. The diagnosis can be established by fine needle cytology in the majority
of cases. Acid-fast bacilli are seen a minority of the cases.
Key words: granulomatous inflammation, mastitis, breast, tuberculosis, Pakistan.
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