FREQUENCY OF HEPATITIS C INFECTION IN DIABETIC PATIENTS

Authors

  • Sobia S. Ali
  • Irum Sabir Ali
  • A H Aamir
  • Zahid Jadoon
  • Saima Inayatullah

Abstract

Background: Diabetic patients are at an increased risk of acquiring Hepatitis C virus (HCV)
infection owing to the nature of the disease and its inherent complications or frequent parentral
exposure. On the other hand HCV infection may itself contribute to the development of Diabetes
Mellitus. The epidemiological evidence of this association has not been studied in Pakistan at a
population level and its exact biological mechanisms are not obvious. Objective of this study was
to study the frequency of HCV infection among adult diabetic patients attending the Hospital.
Methods : The study comprised of 100 Diabetic patients visiting the out patient clinics or admitted
in the medical wards of a Teaching Hospital, in Peshawar. Diabetes was confirmed according to
the new diagnostic criteria based on 2 fasting or 2 random plasma glucose levels of more than 126
milligram per deciliter (mg/dL) and 200 mg/dL respectively. The presence of HCV infection was
confirmed by Enzyme Linked Immuno-Sorbent Assay (ELISA) method. A concise history of the
patient, examination and laboratory findings were recorded on a Performa. Results: Out of the
hundred diabetics, 36% were found to be anti HCV positive and all of them had type II diabetes.
There was no gender difference in the seropositive cases. Serum Glutamic -Pyruvic Transaminase
(SGPT) level was raised in 75% of the positive cases as compared to the 25% of the seronegative
patients. The seropositive cases had a comparatively higher blood sugar level. Conclusion: HCV
infection occurs more often in type II diabetics and further investigations should be done in
diabetic patients with raised SGPT for the presence of chronic HCV infection.
Keywords : Hepatitis C virus, Diabetes mellitus.

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Published

2007-03-01

How to Cite

Ali, S. S., Ali, I. S., Aamir, A. H., Jadoon, Z., & Inayatullah, S. (2007). FREQUENCY OF HEPATITIS C INFECTION IN DIABETIC PATIENTS. Journal of Ayub Medical College Abbottabad, 19(1), 46–49. Retrieved from https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/4290

Issue

Vol. 19 No. 1 (2007): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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