FALCIPARUM MALARIA - AN EXPERIENCE WITH 100 CASES
Abstract
Clinical details and present day problems faced in 100 cases of Falciparum Malaria (FM)are reported. Eleven percent had taken chloroquine prior to reporting to us. The parasite density
lacked correlation with the severity of disease. Pattern of fever varied markedly but 10% were
afebrile throughout and presented only with body ache and malaise. Cerebral malaria was present
in 117c patients. Jaundice was present in 187c patients. Other symptoms were vomiting 447c, severe
headache 127c, pain abdomen 77c, loose motions/dysentery 117c, & cough 87c, while bleeding
diathesis was present in 77c (3 meletia, 2 epistaxis, 1 bleeding gums and 1 haematuria). Severe
anaemia was present in 107c of cases. Splenomegaly was present in 657c, hepatomegaly 297c and
hepatosplenomegaly 217c. Congenital malaria was present in only one (17c) patient. Mild malaria
patients were treated with chloroquine, while severe malaria patients were cured with quinine for
7 days. Blackwater fever was present in 27c.Patients with Blackwater fever were cured with steroids
and chloroquine. 127c patients had chronic malaria. 837c of these patients presented with anaemia.
Self-medication, haphazard therapy and the slogan "Fever May Be Malaria, Take
Chloroquine" can lead to problems in Falciparum Malaria. Clinical immunity and parasite strain
may act as virulence factors.
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