FREQUENCY OF PRIMARY SOLID MALIGNANT NEOPLASMS IN DIFFERENT AGE GROUPS AS SEEN IN OUR PRACTICE
Abstract
Background: To determine in a large series of surgical biopsies, the frequency of varioushistologic types of primary solid malignant neoplasms in males and females in different age
groups. Methods : A retrospective study of 20,000 consecutive surgical biopsies reposted in the
section of histopathology, AKU in 2004. Results: Malignant neoplasms are commonest in the
fifth and sixth decades of life. The commonest malignant neoplasms in the first decade were
Hodgkin's lymphoma and Wilm's tumor in males and females respectively. In the second decade,
osteosarcoma in males and Ewing's sarcoma / PNET in females. In the third decade, colorectal
adenocarcinoma in males and infiltrating Ductal carcinoma of breast in females. In the fourth
decade, squamous cell carcinoma of oral cavity in males and infiltrating ductal carcinoma of
breast in females. In the fifth decade squamous cell carcinoma of oral cavity in males and
infiltrating ductal carcinoma of breast in females. In sixth decade, squamous cell carcinoma of oral
cavity in males and infiltrating ductal carcinoma of breast in females and in the seventh decade,
prostatic adenocarcinoma in males and infiltrating ductal carcinoma of the breast in females.
Above age of 70 years, the commonest malignant were again prostatic adenocarcinoma in males
and infiltrating ductal carcinoma of breast in females. Conclusion: Malignant neoplasms are
commonest in the fourth, fifth and sixth decades of life.
References
Jamal S, Moghal S, Mamoon N, Mushtaq S, Luqman M,
Anwar M. The pattern of malignant tumor registry data
analysis, AFIP, Rawalpindi, Pakistan (1992-2001). J Pak Med
Assoc. 2006; 56(8): 359-62
Cancer registry and clinical data management (CRCDM),
Shaukat Khanum Memorial Cancer Hospital and Research
Centre (SKMCH and RC). Report based on cancer cases
registered at SKMCH and RC from Dec 1994- Dec 2006 and
in 2006. Released June, 2007.
Straus DJ, Filippa DA, Lieberman PH, Koziner B, Thaler HT,
Clarkson BD. The Non- Hodgkin's lymphomas. I. A
retrospective clinical and pathological analysis of 499 cases
diagnosed between 1958 and 1969. Cancer. 1983;51(1):101-9.
Kozakewich H, Perez-Atayde AR, Goorin AM, Wilkinson
RH, Gebhardt MC, Vawter GF. Osteosarcoma in young
children. Cancer. 1991 ; 67(3) : 638-42.
Kissane JM, Askin FB, Nesbit ME Jr, Vietti T, Burgert EO Jr,
Cangir A et al. Sarcoma of bone in childhood: pathologic
aspects. Natl Cancer Inst Monogr. 1981; (56) : 29-41
Jamal S, Mamoon N, Mushtaq S, Luqman M. Pattern of
childhood malignancies: study of 922 cases at Armed Forces
Institute of Pathology (AFIP), Rawalpindi, Paksitan. Asian
Pac J cancer Prev. 2006; 7(3):420-2.
Shah SH, Pervez S, Hasan SH. Frequency of malignant solid
tumors in children. J Pak Med Assoc. 2000; 50(3): 86-88.
Maitra A, Kumar V. Diseases of infancy and childhood.
Tumors and tumor like lesions of infancy and childhood. In:
Pathologic Basis of Disease, Kumar V, Abbas AK, Fausto N
eds. 7th edition 2004, Elsevier Inc: 469-508.
Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world
cancer burden. Globocan 2000. Int J cancer 2001; 94(2) :153-6
Boyle P, Zaridze DG, Smans M. Descriptive epidemiology of
colorectal cancer. Int J Cancer. 1985; 36(1): 9-18
Schlumberger MJ. Papillary and follicular thyroid carcinoma.
N Engl J Med. 1998; 338(5) :297-306
Yang PC, Davis S. Incidence of cancer of the esophagus in the
US by histologic type. Cancer 1988 ; 61(3) : 612-7
Cannistra SA, Niloff JM. Cancer of the uterine cervix. N Engl
J Med. 1996; 334(16): 1030-8.
Nelson WG, De Marzo AM, Isaacs WB. Prostate cancer. N
Engl J Med. 2003; 349(4) : 366-81.
Voigt LF, Weiss NS. E pidemiology of endometrial cancer.
Cancer Treat Res. 1989; 49: 1-21
Bhurgri Y, Bhurgri A, Hassan SH, Zaidi SH, Rahim A,
Sankaranarayanan R et al. Cancer incidence in Karachi,
Pakistan: first results from Karachi Cancer Registry. Int J
Cancer. 2000; 85(3): 325-9.
Bhurgri Y, Bhurgri A, Hasan SH, Usman A, Faridi N, Malik J
et al. Cancer patterns in Karachi division (1998 - 1999). J Pak
Med Assoc. 2002; 52(6):244-6.
Bhurgri Y, Pervez S, Kayani N, Bhurgri A, Usman A, Bashir I
et al. Cancer profile of Larkana, Pakistan (2000 - 2002). Asian
Pac J Cancer Prev. 2006; 7(4):518-21.
Bhurgri Y, Bhurgri A, Pervez S, Bhurgri M, Kayani N,
Ahmed R et al. Cancer profile of Hyderabad, Pakistan 1998 -
Asian Pac J Cancer Prev. 2005; 6(4): 474-80.
Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun
MJ. Cancer statistics, 2003. CA Cancer J Clin. 2003 Jan -
Feb; 53 (1): 5-26.
Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward
E et al.: American Cancer Society. Cancer Statistics, 2004. CA
Cancer J Clin. 2004; 54(1):8-29.
Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor
A et al. Cancer statistics, 2005. CA Cancer J Clin. 2005 Jan -
Feb; 55(1): 10-30.
Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, Thun
MJ. Cancer statistics, 2006. CA Cancer J Clin. 2006;
(2):106-30.
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