LARGE B CELL LYMPHOMA-YEAR BY YEAR
Abstract
Non Hodgkin's Lymphoma (NHL) comprises a group of lymphoproliferative disorders thefrequency of which continues to rise. Although many classification systems exist for
identifying specific histological subtypes, NHL is generally divided into indolent (low-grade)
and aggressive (intermediate- and high-grade) forms. Large B Cell Lymphoma (LBCL) is one
of the commonest aggressive NHLs. The aim of this review is to provide a general overview
of NHL, its clinically practicable cellular classification, epidemiology and in depth overview
of the evolution of treatment of LBCL during the past 5 years. Current guidelines from
National Cancer Institute (NCI), USA and National Institute on Clinical Excellence (NICE),
UK are mentioned and recommendations according to our own set-up are suggested.
Keywords: Non-Hodgkin's Lymphoma, Large B Cell Lymphoma, Rituximab
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