ITRACONOZOLE THERAPY IN TINEA V ERSICOLOR

Authors

  • Imranullah Khan
  • Ahsan Hameed
  • Shad Muhammad Wazir
  • Mian Mujahid Shah

Abstract

The efficacy of itraconazole was assessed in an open trial in 60 patients with wide spread disseminated lesions of
Tinea versicolor confirmed by direct microscopy. The patients were allocated randomly to one of the two treatment
regimens. 200 mg once daily for 7 days or 100 mg once daily for 15 days. On assessment 3 weeks after the end of the
treatment. 50 patients were healed. 4 had mild residual lesions. 4 had considerable residua! lesions, and 2 had
relapsed. Two patients reported pain in the abdomen. Two patients reported nausea, vomiting and dyspepsia. Two
patients had mild elevation of SOOT, and SOFT. Conclusion: Treatment of tinea versicolor with itraconozole 200mg
day for 7 days or l00 mg day for 15 days is recommended.

References

Robert s, S.O.B, pitrysporum orbiculare incidence and

distribution on clinically normal skin. Br. J. of

Dermatology (1969a) 81:264.

Faergman, J. and Fredikson, T. Tinea versicolor with

regard to seborrheic dermatitis. Archives of

Dermatology, 1979;115: 966.

Burke, R.C. Tinea versicolor: Susceptibility factors and

experimental infections in human beings. Journal of

investigative dermatology (1961); 36: 389.

Savin, R.C, Systemic itraconozole in tinea vesicular: a

double blind examination and 1 year follow up. Journal

of American Academy of Dermatology 1984; 10: 824.

Janssen Pharmaceutica (1984) RS 1211 Basic Medical

Information Brochure, August 1984

Del Palacio Hernanz A. Delgado Vicente S. Menendez

Romes. Randomized comparative clinical trial of

itraconozole and selenium sulphide shampoo for the

treatment of tinea versicolor Rev Infect. Dis. 1987.

(Suppl-l)

Downloads

How to Cite

Khan, I., Hameed, A., Wazir, S. M., & Shah, M. M. (1999). ITRACONOZOLE THERAPY IN TINEA V ERSICOLOR. Journal of Ayub Medical College Abbottabad, 11(1). Retrieved from https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/5089