• Muhammad Arshad The Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad
  • Iqra Manzoor University Institue of Radiological Sciences and Medical Imaging Technology, Lahore
  • Khalid Hussain Memon University Institue of Radiological Sciences and Medical Imaging Technology, Lahore
  • Asif Haider University Institue of Radiological Sciences and Medical Imaging Technology, Lahore
  • Umer Aziz Khan NIMS Teaching Hospital Abbottabad
  • Iraj Nayab Hazara University, Mansehra
  • Zareen Fatima University Institue of Radiological Sciences and Medical Imaging Technology, Lahore



Cirrhosis, Fibroscan, Hepatic events, Liver stiffness measurement Fibrosis


Background: Hepatitis C is a diverse illness that causes significant death and morbidity. The hepatitis C virus infects hundreds of millions of individuals globally (HCV). More than 80% of those infected develop chronic infection; the remaining 10–20% recover spontaneously through natural immunity. Acute hepatitis is only icteric in 20% of individuals and is seldom severe. Methods: A pilot study was conducted at INOR hospital Abbottabad. Eleven hepatitis C positive and 10 hepatitis C negative participants were included in the study. Results: A significant difference correlation was found between viral load and SWE quantification for fibrosis stage in Kilo-Pascal, r= 0.904 (p-value=0.000 <a=0.05). HCV positive patients showed a viral load of (Mean±SD) 128,185.8±153,719.1. Conclusion: Although a biopsy is considered to be gold standard for determining the degree of damage caused by chronic viral hepatitis, it is far from perfect. Liver elastography is an intriguing technique that can help physicians make difficult decisions while treating viral hepatitis. This study showed that fibrotic changes of liver are directly proportional to the presence of viral load in blood. The greater the viral load more severe fibrosis will be seen. Age also plays a role in severity of fibrosis, however, more studies on larger population is required to support this statement.

Author Biographies

Muhammad Arshad, The Institute of Nuclear Medicine, Oncology and Radiotherapy, Abbottabad

Technologist Radiology INOR

Iqra Manzoor, University Institue of Radiological Sciences and Medical Imaging Technology, Lahore


Khalid Hussain Memon, University Institue of Radiological Sciences and Medical Imaging Technology, Lahore


Asif Haider, University Institue of Radiological Sciences and Medical Imaging Technology, Lahore


Umer Aziz Khan, NIMS Teaching Hospital Abbottabad


Iraj Nayab, Hazara University, Mansehra


Zareen Fatima, University Institue of Radiological Sciences and Medical Imaging Technology, Lahore



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