PYREXIA-INDUCED BRUGADA PHENOCOPY

Authors

  • Nauman Khalid
  • Lovely Chhabra
  • Jeffrey Kluger

Abstract

Brugada syndrome (BS) is characterized by a typical electrocardiographic (ECG) pattern in the right precordial leads and a predisposition to develop ventricular arrhythmias. Mutations in α-subunit of cardiac sodium channel (SCN5A) have been linked to BS. Experimental studies in the literature suggest that this dysfunction of the mutated channel can be temperature sensitive. Several antiarrhythmics have been used in the management of BS but Implantable Cardioverter Defibrillators (ICD) remains the only effective treatment. We herewith present the case report of a 62-year-old man who developed a type-2 Brugada ECG phenotype in a febrile state with complete resolution once the fever subsided.Keywords: Brugada syndrome; Electrocardiography; Brugada pattern

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Published

2015-03-01