PATTERN OF BREAST CANCER: EXPERIENCE AT AYUB TEACHING HOSPITAL, ABBOTTABAD
DOI:
https://doi.org/10.55519/JAMC-04-12089Abstract
Background: Breast cancer is the most common malignancy found in females all over the world and the second leading cause of cancer death in European countries. The purpose of this study was to find out the pattern of disease presentation in our region where a proper tumour registry system is lacking. Methods: This descriptive study was carried out in the Department of Surgery, Ayub Teaching Hospital Abbottabad, from July 2021 to June 2022. All female patients with biopsy-proven breast cancer were included in the study: benign lumps, refused to enrol, and those who were lost to follow-up were excluded. Results: A total of 87 patients with carcinoma breast were included: 92 % (n=80) had invasive ductal carcinoma. Axillary lymph nodes were involved in 88.5% (n=77), 75.8% of the tumours, (n=66), were Grade 2, 34.5% (n=30) were in the 40-49 years age group, and 30 % (n=27) of the disease was categorized as Stage III or IV. In 55 % (n=48), the tumour was on the right side and in 39% (n=34), the upper outer quadrant was involved. Most of the patients, 90.8% (n=79), were married and had used contraceptive measures. Only 19.5% of patients (n=17), had a history of nipple discharge and 56% (n=49) had a positive family history: 71% (n=62) had nipple retraction, and 54% (n=47), proved to be ER PR positive. Conclusion: Our patients presented late: axilla was commonly involved and a third had advanced disease. Screening and community awareness programs may help in early detection. Hormone use for contraception needs to be weighed carefully. Better data collection may help in designing screening and care programs.
References
Naeem M, Khan N, Aman Z, Nasir A, Samad A, Khattak A. Pattern of breast cancer: experience at Lady Reading Hospital, Peshawar. J Ayub Med Coll Abbottabad 2008;20(4):22-5.
Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Zackrisson S, Senkus E. Early breast cancer: ESMO Clinical practice guidelines for diagnosis, treatment and follow up. Ann Oncol 2019;30(8):1194-1220.
Yip CH, Taib NA, Mohamed I. Epidemiology of breast cancer in Malaysia. Asian Pac J Cancer Prev 2006;7(3):369- 74.
Sohail S, Alam SN. Breast cancer in Pakistan - awareness and early detection. J Coll Physicians Surg Pak 2007;17(12):711-2.
Khan NH, Duan SF, Wu DD, Ji XY. Better Reporting and Awareness Campaigns Needed for Breast Cancer in Pakistani Women. Cancer Manag Res 2021;13:2125-2129. doi: 10.2147/CMAR.S270671.
Aslam MN, Ansari AK, Siddique A. Carcinoma breast, late presentation - a big concern. Ann King Edward Med Uni 2006;12(2):317-9.
Batool, M, Arian, M, Gardezi, J. (2005). An experience with breast disease in a surgical unit of a teaching hospital of Lahore. Biomedica. 2005;21:108-12.
Gilani GM, Kamal S, Akhter AS. A differential study of breast cancer patients in Punjab, Pakistan. J Pak Med Assoc 2003;53(10):478-81.
Siddiqui MS, Kayani N, Sulaiman S, Hussainy AS, Shah SH, Muzaffar S. Breast carcinoma in Pakistani females: a morphological study of 572 breast specimens. J Pak Med Assoc 2000 Jun;50(6):174-7.
Mamoon N, Sharif MA, Mushtaq S, Khadim MT, Jamal S. Breast carcinoma over three decades in northern Pakistan--are we getting anywhere? J Pak Med Assoc 2009;59(12):835-8
Hanby AM. The pathology of breast cancer and the role of the histopathology laboratory. Clin Oncol (R Coll Radiol) 2005;17(4):234-9.
Leong SP, Shen ZZ, Liu TJ, Agarwal G, Tajima T, Paik NS, et al. Is breast cancer the same disease in Asian and Western countries? World J Surg 2010;34(10):2308-24.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Shawana Asad, Sher Ali Khan, Fawad Ahmad Khan, Mir Jalal-ud-din, Ghazala Bhatti, Haider Kamran
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.
