• Munir Ahmad Abbasi
  • Amir Suleman
  • Naseer Ahmed
  • Haidar Zaman


Background: Kartagener Syndrome is characterized by ciliary dyskinesia and is inherited in autosomal recessive manner. It occurs in 1:20,000–30,000 live births in general population. Its prevalence varies from region to region. Methods: This case series describes four patients of Kartagener Syndrome who were diagnosed in the departments of medicine and pulmonology between year 2009 and 2013. Results: The age of youngest patient was 15 years while the oldest patient was 19 years old. All of them were males. Mean age was 17.5 years. They had presented with history of shortness of breath and productive cough. One of them had presented with rhinorrhea and nasal blockage as the main symptom. Conclusion: Although Kartagener Syndrome is often thought of as a rare disorder, yet it might not be as rare as it is thought of. Considering this and the fact that half of the patients with Kartagener Syndrome do not have situs inversus, large scale studies with family trees are required to trace patients with Kartagener Syndrome.Keywords: Kartagener Syndrome, Autosomal Recessive, Dextrocardia. Bronchiectasis


M Kartagener. Zur Pathogenese der Bronchiektasen. Beitr Klin Tuberk Spezifischetn Tuberk Forsch 1933;83:489–501.

Ortega HAV, Vega N de A, Santos BQ dos, Maia GT da S. Discinesia ciliar primária: considerações sobre seis casos da síndrome de Kartagener. J Brasileiro de Pneumol 2007;33(5):602–8

Whitelaw A, Evans A, Corrin B. Immotile cilia syndrome: a new cause of neonatal respiratory distress. Arch Dis Child 1981;56(6):432–5

Erling V, Jalil F, Hanson LA, Zaman S. The impact of climate on the prevalence of respiratory tract infections in early childhood in Lahore, Pakistan. J Public Health Med 1999;21(3):331–9.

Afzelius BA. Genetics and pulmonary medicine. 6. Immotile cilia syndrome: past, present, and prospects for the future. Thorax 1998;53(10):894–7

Kashif A, Masud M, Manzoor SM, Haneef S. Kartagener’s syndrome and acute appendicitis. J Ayub Med Coll Abbottabad 2010;22(1):176–7.

Aziz S, Soomro GB, Luck NH, Hussain SM, Mirza R, Naqvi SAA, et al. Biliary atresia with situs inversus: an experience shared. J Pak Med Assoc 2005;55(8):350–2

Babar KS, Khan H, Ismail Y, Azim Q, Fawad M. Kartagener Syndrome. Gomal J Med Sci. 2013;11(2):239–41.

Mahsud I, Din S. Kartagener’s Syndrome. Gomal J Med Sci 2006;4(2):79–81.

Tayeb M, Khan F, Rauf F. Situs inversus totalis with perforated duodenal ulcer: a case report. J Med Case Report 2011;5(1):279

Zulqarnain S, Pesola G. A Rare Cause of Adult Bronchiectasis. Chest. 2011;140(4_MeetingAbstracts):9A.

Skeik N, Jabr F. Kartagener syndrome. Int J Gen Med 2011;4:41–3.

Rosen MJ. Chronic cough due to bronchiectasis: ACCP evidence-based clinical practice guidelines. Chest 2006;129(1 Suppl):122S–131S.

Gupta S, Handa KK, Kasliwal RR, Bajpai P. A case of Kartagener’s syndrome: Importance of early diagnosis and treatment. Indian J Hum Genet 2012;18(2):263–7




Most read articles by the same author(s)

1 2 > >>