• Muhammad Waqas Shifa International Hospital Islamabad
  • Durre Shohab Shifa International Hospital Islamabad
  • Mohammad Athar Khawaja Shifa International Hospital Islamabad
  • Afifa Masood Shifa International Hospital Islamabad
  • Muhammad Waqas Iqbal Shifa International Hospital Islamabad
  • Saeed Akhter Shifa International Hospital Islamabad


Background: This study was conducted to determine the outcome of trans-rectal ultrasound (TRUS) guided biopsy of prostate for the detection of prostatic carcinoma in a single tertiary care hospital in Pakistan. Methods: This is a retrospective study including three hundred and eighty-three patients who underwent trans rectal ultrasound guided biopsy of prostate in a single tertiary care hospital. Indications for biopsy were raised prostate specific antigen (PSA), abnormal digital rectal examination (DRE) and/or both. Twelve core biopsy of prostate was done. Results: The overall detection rate of prostate cancer was 59%. Prostate cancer detection in various PSA ranges of 0-3.99, 4–9.99, 10–19.99 and >20 ng/ml are 22.22%, 37.88%, 50.0% and 89.9%. PSA density >0.15ng/ml2 can diagnose 74.5% of patients with cancer. Prostate cancer detection rate based on abnormal DRE is 64.6% compared to 60.8% detected by PSA>4 ng/ml. Conclusion: In conclusion raised PSA, smaller prostate volume, abnormal DRE and raised PSA density are associated with greater chances of detection of prostate carcinoma.Keywords: Digital rectal examination; Prostate cancer; Prostate Specific antigen; Prostate volume, Trans rectal ultrasound

Author Biographies

Muhammad Waqas, Shifa International Hospital Islamabad

Post graduate Resident Urology department Shifa international Hospital Islamabad

Durre Shohab, Shifa International Hospital Islamabad

Assistent consultant  Urology department Shifa international Hospital Islamabad

Mohammad Athar Khawaja, Shifa International Hospital Islamabad

consultant  Urology department Shifa international Hospital Islamabad

Afifa Masood, Shifa International Hospital Islamabad

Post graduate trainee  Urology department Shifa international Hospital Islamabad

Muhammad Waqas Iqbal, Shifa International Hospital Islamabad

Post graduate trainee  Urology department Shifa international Hospital Islamabad

Saeed Akhter, Shifa International Hospital Islamabad

Consultant  Urology department Shifa international Hospital Islamabad


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