EFFICACY OF TOPICAL CLOTRIMAZOLE IN TREATMENT OF OTOMYCOSIS

Authors

  • Farida Khan
  • Raza Muhammad
  • Muhammad Riaz Khan
  • Fazal Rehman
  • Johar Iqbal
  • Munib Khan
  • Gohar Ullah

Abstract

Background: Otomycosis is a common condition affecting external ear and ears with chronic suppurative otitis media, and has a tendency for recurrence. Objective of this study was to determine the efficacy of topical clotrimazole in the treatment of otomycosis. Methods: This descriptive study was conducted at the outpatient department of ENT, Ayub Teaching Hospital Abbottabad, from Jul 2012 to Dec 2012. A total of 101 patients were included in this study. The results were compared and analysed regarding age, gender, presenting complaints and efficacy of clotrimazole. Results: A total of 101 patients of otomycosis were included in the study. Male to female ratio was 0.71:1. Patients of 15 years and above were included in the study. Adults were more affected by otomycosis than the younger age group. The efficacy of clotrimazole in treatment of otomycosis was observed in 89 (94.12%) while in 12 (5.88%) patients no efficacy was seen. Age and gender have no role in efficacy of Clotrimazole in treatment of Otomycosis. Conclusion: Topical clotrimazole is effective in the treatment of Otomycosis.Keywords: Otomycosis, Clotrimazole

References

Malik AA, Malik SN, Aslam MA, Rasheed D. Comparative efficacy of topical clotrimazole and 3% salicylic acid in otomycosis. Rawal Med J 2012;13(37):46–9.

Pontes SVZ, Silva FDA, Lima OE, Guerra HM, Oliveira CMN, Carvalho PFM. Otomycosis. Braz J Otorhinolaryngol 2009;75:367–70.

Munguia R, Daniel JS. Ototopical antifungals and otomycosis. Int J Pediatr Otorhinolaryngol 2008;2:453–9.

Mahmoudabadi AZ. Mycological studies in 15 cases of otomycosis. Pak J Med Sci 2006;22:486–8.

Pakshir K, Sabayan B, Javan H, Karamifar K. Mycoflora of human external auditory canal in Shiraz. Iran Red Crescent Med J 2008;10(1):27–9.

Moghadam YA, Asadi AM, Dehghani R, Mahmoudabadi ZA, Rayegan F, Hooshyar H, et al. Evaluating the effect of a mixture of alcohol and acetic acid for otomycosis. Jundishapur J Microbiol 2010;3:66–70.

Viswanatha B, Naseeruddin K. Fungal infections of the ear in immunocompromised host. Mediterr J Hematol Infect Dis 2011;3(1):e2011003.

Chalabi EY, Ahmed TS. The role of various out patients aural toileting procedures in the treatment of otomycosis. J Zankoy Sulaimani 2010;13:39–48.

Jackman AR, Ward R, April M, Bent J. Topical antibiotic induced otomycosis. Int J Pediatr Otorhinolaryngol 2005;69:857–60.

Ahmed Z, Hafeez A, Zahid T, Jawaid MA, Matiullah S, Marfani MS. Otomycosis: Clinical presentation and management. Pak J Otolaryngol 2010;26:78–80.

Sterm JC, Lucente FE. Otomycosis. Ear Nose Throat J 1988;67:804–10.

Pradhan B, Tuladhar NR, Amatya RM. Prevalence of otomycosis in outpatient department of otolaryngology in Tribhuvan University Teaching Hospital, Kathmandu, Nepal. Ann Otol Rhinol Laryngol 2003;112:384–7.

Kaur R, Mittal N, Kakkar M, Aggarwal AK, Mathur MD. Otomycosis: a clinicomycologic study. Ear Nose Throat J 2000;79:606–9.

Ozcan KM, Ozcan M, Karaarslan A, Karaarslan F. Otomycosis in Turkey: predisposing factors, etiology and therapy. J Laryngol Otol 2003;117:39–42.

Ho T, Vrabec JT, Yoo D, Coker NJ. Otomycosis: clinical features and treatment implications. Otolaryngol Head Neck Surg 2006;135:787–91.

Bassiouny A, Kamel T, Moawad MK, Hindawy DS. Broad spectrum antifungal agents in otomycosis. J Laryngol Otol 1986;100:867–73.

Kurnatowski P, Filipiak A. Otomycosis: prevalence, clinical symptoms, therapeutic procedure. Mycosis 2001;44:472–9.

Youssef YA, Abdou MH. Studies on fungus infection of the external ear. II. on the Chemotherapy of Otomycosis. J Laryngol Otol 1967;81:1005–12.

Ologe FE, Nwabuisi C. Treatment outcome of otomycosis in Ilorin, Nigeria. West Afr J Med 2002;21:34–6.

Jadhav VJ, Pal M, Mishra GS. Etiological significance of Candida albicans in otitis externa, Mycopathologia. 2003;156:313–5

Downloads

Published

2013-06-01

Most read articles by the same author(s)

1 2 > >>