• Nazli Hameed
  • Muhammad Asghar Ali


Background: Anovulatory infertility due to polycystic ovarian syndrome (PCOS) remains thecommonest cause among women of reproductive age group. Although clomiphene citrate (CC) remainsthe first choice treatment in addition to other medical therapies, laparoscopic ovarian drilling (LOD) israpidly gaining acceptance as a second line management in patients who failed to respond to CC. Thisstudy was done to evaluate the efficacy of LOD in management of PCOS related infertility. Methods:This was a descriptive study conducted at CMH Peshawar, CMH Kharian, and PAF Hospital Mushaf,from 2004 to 2011. It included 69 patients who underwent LOD for anovulatory infertility after beingdiagnosed as PCOS. Patients were diagnosed on the basis of their clinical, hormonal and ultrasonicfindings. Age of the patients, features suggestive of hyperandrogenism, body mass index (BMI),duration of infertility, and LH/FSH ratio were noted. Patients were followed post-operatively for oneyear. Results: Overall ovulation rate was 82.61% after LOD. Thirty-one out of 69 patients ovulatedspontaneously within first 6 weeks after LOD while 26 patients ovulated on getting treatment with CCin addition to LOD. Thirty-three (47.82%) patients conceived in their first year after surgery. About54% of patients reported improvement in their symptoms related to hyperandrogenism. Conclusion:LOD is an established and safe method as a second line treatment for PCOS related infertility.Keywords: Polycystic Ovarian Syndrome, Laparoscopic ovarian drilling


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