PRIMARY ALVEOLAR PROTEINOSIS
Abstract
A 35 years old man presented with primary pulmonary alveolar proteinosis who was admitted tochest unit of ATH through casualty department. Before he came to our ward he was treated withdifferent antibiotics including anti-tuberculosis drugs for a month at least. But his symptoms didnot improve rather his dyspnoea got worse. He was misdiagnosed till histopathology revealed thathe has pulmonary alveolar proteinosis. With this background we briefly review clinical features,diagnosis and treatment of this rare disease.Keywords: Pulmonary alveolar proteinosis, Dyspnoea, anti-tuberculosis drugsReferences
Inove Y, Trapnell BC, Tazwa R, Arai T, Takada T, Hizawa N, et
al, Characteristics of large cohort of patients with autoimmune
pulmonary alveolar proteinosis in Japan. Amj Respir Crit Care
Med 2008;177:752–62.
Seymour JF, presnell JJ. Pulmonary alveolar proteinosis progress
in the first 44 years. Amj Respir crit care Med 2002;166:215–35.
Frazier AA, Franks TJ, Cook Eo, Mohammed TL, Pugatch RD,
Galvin JR. From the archives of AFIP; Pulmonary alveolar
proteinosis Radiographics 2008;28:883–99.
Suratt PM, winn WC Jr, Brody AR, Brody AR, Bolton WK,
Giles RD. Acute silicosis in tomb stone sand blasters. Am Rev
Respir dis 1977;115:521–9.
Doan ML,Guillerman RP, Dishop MK, Nogee LM, Langston C,
Mallory GB, et al. Clinical, radiological and pathological features
of ABCAz mutation in children. Thorax 2008;63:366–73.
Wang BM, Stern EJ, Schmidt RA, Pierson DJ. Diagnosing
pulmonary alveolar proteinosis. A review and an update. Chest
;111:460–6.
Venkateshiah SB, Yan TD, Bonfield TL, Thomassen MJ,
Meziane M, Czich C, et al. An open label trial of granulocyte
macrophage colony stimulating factor therapy for moderate
symptomatic pulmonary alveolar prteinosis. Chest
;130;227–37.
Tazawa R, Trapnell BC, Inoue Y, Arai T, Takada T, Nasuhara Y,
et al. Inhaled Granulocyte/macrophage colony stimulating factor
as therapy for pulmonary alveolar proteinosis. Am J Respi Crit
Care med 2010;181(12):1345–54.
Downloads
Published
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.